{"id":848,"date":"2026-05-25T03:49:50","date_gmt":"2026-05-25T03:49:50","guid":{"rendered":"https:\/\/wuhantopmiraclepeptides.com\/?post_type=product&#038;p=848"},"modified":"2026-06-27T18:08:58","modified_gmt":"2026-06-27T18:08:58","slug":"ara-290-16mg","status":"publish","type":"product","link":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/product\/ara-290-16mg\/","title":{"rendered":"ARA-290 (16mg)"},"content":{"rendered":"<h1><span class=\"\">ARA-290 (16mg) Research Peptide: An EPO\u2011Derived Agonist of the Innate Repair Receptor for Neuroprotection &amp; Inflammation Studies<\/span><\/h1>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">If your research investigates neuroprotection, tissue repair, or the modulation of inflammatory pathways,\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0\u2014 also known as cibinetide \u2014 offers a precisely defined and mechanistically distinct synthetic tool. ARA-290 is an 11\u2011amino\u2011acid synthetic peptide engineered to replicate the three\u2011dimensional structure of the helix B surface domain of erythropoietin (EPO)<\/span><span class=\"\">. <\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Unlike full\u2011length EPO, which drives red blood cell production through the classical homodimeric EPO receptor, ARA-290 was specifically designed to bind selectively to the non\u2011haematopoietic EPO receptor \u2014 a heterodimeric complex of EPOR and the beta\u2011common receptor (\u03b2cR, CD131) termed the\u00a0<\/span><strong><span class=\"\">innate repair receptor (IRR)<\/span><\/strong><span class=\"\">. This receptor mediates EPO&#8217;s tissue\u2011protective and anti\u2011inflammatory effects while being pharmacologically separable from the erythropoietic pathway<\/span><span class=\"\">. This makes\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0a valuable tool for laboratories investigating neuroprotection, inflammation, tissue repair, and metabolic regulation without the confounding variable of erythropoiesis.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">At\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, we supply high\u2011purity\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0to research institutions and wholesale buyers across the\u00a0<\/span><strong><span class=\"\">United Kingdom, France, Germany, Spain, Sweden, Italy, and the USA<\/span><\/strong><span class=\"\">. Every batch is lyophilised, HPLC\u2011verified to \u226598% purity, and accompanied by a Certificate of Analysis (COA), ensuring your investigations into neuroprotection, tissue repair, and inflammatory signalling begin with uncompromising quality.<\/span><\/p>\n<h2><span class=\"\">What Is ARA-290 and How Does It Work?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">To fully appreciate the research potential of\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">, it is essential to understand its biochemical design and the precise mechanism by which it exerts its tissue\u2011protective effects.<\/span><\/p>\n<h3><span class=\"\">The 11\u2011Amino\u2011Acid EPO\u2011Derived Peptide<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">ARA-290 (cibinetide) is a synthetic linear peptide composed of 11 amino acids<\/span><span class=\"\">. Its sequence is\u00a0<\/span><strong><span class=\"\">{Glp}\u2011Glu\u2011Gln\u2011Leu\u2011Glu\u2011Arg\u2011Ala\u2011Leu\u2011Asn\u2011Ser\u2011Ser<\/span><\/strong><span class=\"\">\u00a0(shortened as {Glp}\u2011EQLERALNSS)<\/span><span class=\"\">. Its molecular formula is\u00a0<\/span><strong><span class=\"\">C\u2085\u2081H\u2088\u2084N\u2081\u2086O\u2082\u2081<\/span><\/strong><span class=\"\">, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">1257.31 g\/mol<\/span><\/strong><span class=\"\">. It has a CAS number of\u00a0<\/span><strong><span class=\"\">1208243-50-8<\/span><\/strong><span class=\"\">\u00a0and a PubChem CID of\u00a0<\/span><strong><span class=\"\">91810664<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The peptide was engineered from the helix\u2011B surface of the EPO molecule, identifying an 11\u2011amino\u2011acid sequence that selectively activates the tissue\u2011protective receptor without binding the classical homodimeric EPOR<\/span><span class=\"\">. This separation of function \u2014 between erythropoietic and tissue\u2011protective activities \u2014 was a key scientific insight that enabled the development of ARA-290<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">Mechanism of Action: Selective Innate Repair Receptor Agonism<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The biological activity of\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is mediated through its selective activation of the innate repair receptor (IRR):<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Receptor Targeting:<\/span><\/strong><span class=\"\">\u00a0ARA-290 binds selectively to the non\u2011haematopoietic EPO receptor, a heterodimeric complex composed of EPOR and the beta\u2011common receptor (\u03b2cR, CD131)<\/span><span class=\"\">. This receptor is distinct from the classical homodimeric EPOR that drives erythropoiesis<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Tissue Protection Without Erythropoiesis:<\/span><\/strong><span class=\"\">\u00a0By engaging the IRR, ARA-290 activates the tissue\u2011protective and anti\u2011inflammatory arm of the EPO signalling system without stimulating red blood cell production<\/span><span class=\"\">. This addresses the central challenge in EPO\u2011based research: achieving tissue\u2011protective effects without erythropoiesis<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Anti\u2011Inflammatory and Anti\u2011Apoptotic Signalling:<\/span><\/strong><span class=\"\">\u00a0ARA-290 reduces inflammation and fibrosis<\/span><span class=\"\">, suppresses neuronal apoptosis<\/span><span class=\"\">, and mediates tissue protection through the \u03b2\u2011common receptor<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Short Half\u2011Life, Sustained Effects:<\/span><\/strong><span class=\"\">\u00a0Despite a plasma half\u2011life of approximately 2 minutes, ARA-290 activates a molecular switch that triggers sustained biological effects observed in multiple preclinical models and clinical trials<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Research Note: The Innate Repair Receptor<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The IRR is suggested to be a point of integration between the immune system and pain signalling (via nociception)<\/span><span class=\"\">. ARA-290 was designed to bind the IRR selectively, and this receptor configuration \u2014 first described in a landmark 2004 study in\u00a0<\/span><em><span class=\"\">PNAS<\/span><\/em><span class=\"\">\u00a0\u2014 mediates EPO&#8217;s neuroprotective and cytoprotective effects<\/span><span class=\"\">.<\/span><\/p>\n<h2><span class=\"\">Key Research Applications for ARA-290 (16mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is a versatile tool with applications spanning several domains of biomedical research.<\/span><\/p>\n<h3><span class=\"\">1. Neuroprotection &amp; Ischaemic Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">ARA-290 has demonstrated significant neuroprotective effects in models of cerebral ischaemia. Research has demonstrated:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cerebral Ischaemic Stroke:<\/span><\/strong><span class=\"\">\u00a0ARA-290 exerts a neuroprotective action against cerebral ischaemic injury by suppressing neuronal apoptosis and inflammatory reactions in mice without motivating splenomegaly and erythropoiesis<\/span><span class=\"\">. The neuroprotective effect is mediated via the \u03b2\u2011common receptor<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Neuropathic Pain:<\/span><\/strong><span class=\"\">\u00a0ARA-290 dose\u2011dependently reduced allodynia coupled to suppression of the spinal microglia response<\/span><span class=\"\">. Phase II trials in sarcoidosis\u2011associated small\u2011fiber neuropathy showed improvements in neuropathic pain scores and corneal nerve fibre density<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Experimental Autoimmune Encephalomyelitis:<\/span><\/strong><span class=\"\">\u00a0ARA-290 demonstrated neuroprotective effects equivalent to EPO in a rat model of EAE<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">2. Inflammation &amp; Immune Modulation Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">ARA-290&#8217;s anti\u2011inflammatory properties make it a valuable tool for studying inflammatory signalling:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Chronic Stress\u2011Induced Depression:<\/span><\/strong><span class=\"\">\u00a0ARA-290 ameliorated chronic stress\u2011induced depression\u2011like behaviour in mice through, at least partially, its anti\u2011inflammatory effects<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cardiac Inflammation:<\/span><\/strong><span class=\"\">\u00a0ARA-290 reduces cardiac inflammation, attenuates age\u2011associated declines in heart function, and prolongs healthspan<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Inflammatory Pathway Suppression:<\/span><\/strong><span class=\"\">\u00a0ARA-290 mediates tissue protection by reducing inflammatory and fibrotic responses via signalling through the EPOR\/CD131 heterodimeric receptor<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">3. Metabolic &amp; Diabetes Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">ARA-290 has been investigated for its effects on metabolic control:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Type 2 Diabetes:<\/span><\/strong><span class=\"\">\u00a0ARA-290, a non\u2011erythropoietic peptide engineered from EPO, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Fat Mass and Glucose Tolerance:<\/span><\/strong><span class=\"\">\u00a0Non\u2011erythropoietic EpoR agonist ARA-290 decreased fat mass and increased glucose tolerance without increasing EPO\u2011stimulated erythropoiesis in mouse models<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">4. Tissue Repair &amp; Regenerative Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">ARA-290 has been studied for its tissue\u2011protective effects across multiple organ systems:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Acute Kidney Injury:<\/span><\/strong><span class=\"\">\u00a0ARA-290 exerts beneficial effects in preclinical models of acute kidney injury<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Emphysema:<\/span><\/strong><span class=\"\">\u00a0ARA-290 has demonstrated beneficial effects in models of emphysema<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Endothelial Colony\u2011Forming Cells:<\/span><\/strong><span class=\"\">\u00a0ARA-290 enhances the proliferation, migration, and resistance to H\u2082O\u2082\u2011induced apoptosis of endothelial colony\u2011forming cells<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">5. Frailty &amp; Healthspan Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">ARA-290 has been studied for its potential to ameliorate frailty and preserve healthspan:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Frailty Amelioration:<\/span><\/strong><span class=\"\">\u00a0Administration of ARA-290 reduces cell and tissue inflammation, mitigates structural and functional changes within the cardiovascular system, leading to amelioration of frailty and preserved healthspan<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"\">Chemical &amp; Physical Specifications<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Accurate characterisation of\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is essential for reproducible experimental design.<\/span><\/p>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Parameter<\/span><\/th>\n<th><span class=\"\">Specification<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong><span class=\"\">Common Names<\/span><\/strong><\/td>\n<td><span class=\"\">ARA-290, Cibinetide, PH-BSP<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Sequence<\/span><\/strong><\/td>\n<td><span class=\"\">{Glp}\u2011Glu\u2011Gln\u2011Leu\u2011Glu\u2011Arg\u2011Ala\u2011Leu\u2011Asn\u2011Ser\u2011Ser<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Shortened Sequence<\/span><\/strong><\/td>\n<td><span class=\"\">{Glp}\u2011EQLERALNSS<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Formula<\/span><\/strong><\/td>\n<td><span class=\"\">C\u2085\u2081H\u2088\u2084N\u2081\u2086O\u2082\u2081<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Weight<\/span><\/strong><\/td>\n<td><span class=\"\">~1257.31 g\/mol<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">CAS Number<\/span><\/strong><\/td>\n<td><span class=\"\">1208243\u201150\u20118<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">PubChem CID<\/span><\/strong><\/td>\n<td><span class=\"\">91810664<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Purity<\/span><\/strong><\/td>\n<td><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0(HPLC verified)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Appearance<\/span><\/strong><\/td>\n<td><span class=\"\">White to off\u2011white lyophilised powder<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Solubility<\/span><\/strong><\/td>\n<td><span class=\"\">Soluble in sterile water and sterile PBS (pH 5\u20117)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Lyophilised)<\/span><\/strong><\/td>\n<td><span class=\"\">\u201320\u00b0C, sealed, protected from light; stable for up to 2 years<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Reconstituted)<\/span><\/strong><\/td>\n<td><span class=\"\">2\u20118\u00b0C for short\u2011term use; single\u2011use aliquots at \u201320\u00b0C for up to 3 months<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Note:<\/span><\/strong><span class=\"\">\u00a0The 16\u202fmg mass refers to the weight of the peptide in its lyophilised form. ARA-290 is typically supplied as a TFA salt, which enhances aqueous solubility<\/span><span class=\"\">. The peptide has a plasma half\u2011life of approximately 2 minutes<\/span><span class=\"\">, but its protective effects are sustained through activation of the innate repair receptor<\/span><span class=\"\">.<\/span><\/p>\n<\/blockquote>\n<h2><span class=\"\">Reconstitution &amp; Handling Protocol for ARA-290 (16mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Proper reconstitution of\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is critical for maintaining its structural integrity and biological activity.<\/span><\/p>\n<h3><span class=\"\">Step 1 \u2013 Preparation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Bring the sealed ARA-290 vial and your chosen diluent (sterile bacteriostatic water or sterile PBS, pH\u202f5\u20117) to room temperature.\u00a0<\/span><em><span class=\"\">Condensation can degrade the lyophilised powder.<\/span><\/em><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Clean your work surface with 70% ethanol and lay out sterile syringes, alcohol wipes and a clean work mat.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 2 \u2013 Vial Sanitisation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Wipe the rubber stopper of the ARA-290 vial with a fresh 70% ethanol wipe. Allow the alcohol to evaporate completely before piercing.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 3 \u2013 Reconstitution<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Draw your desired volume of diluent into a sterile syringe. A common starting concentration for research applications is\u00a0<\/span><strong><span class=\"\">16\u202fmg per 1.6\u202fmL of diluent<\/span><\/strong><span class=\"\">, yielding a\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">\u00a0stock solution.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Insert the needle and slowly inject the diluent\u00a0<\/span><strong><span class=\"\">against the inner glass wall<\/span><\/strong><span class=\"\">. Do not spray directly onto the lyophilised powder.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Gently swirl the vial until the solution is clear and fully dissolved.\u00a0<\/span><strong><span class=\"\">Do not shake vigorously<\/span><\/strong><span class=\"\">, as shaking can cause denaturation.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 4 \u2013 Aliquoting &amp; Storage<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Immediately after dissolution, aliquot the reconstituted ARA-290 into single\u2011use sterile vials.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Store aliquots at \u201320\u00b0C.\u00a0<\/span><strong><span class=\"\">Avoid repeated freeze\u2011thaw cycles<\/span><\/strong><span class=\"\">, as peptides are susceptible to degradation.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Once thawed, store at 2\u20118\u00b0C and use within a short period.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Concentration Reference Table<\/span><\/h3>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Vial Mass<\/span><\/th>\n<th><span class=\"\">Diluent Volume<\/span><\/th>\n<th><span class=\"\">Final Concentration<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">16\u202fmg<\/span><\/td>\n<td><span class=\"\">1.6\u202fmL<\/span><\/td>\n<td><span class=\"\">10\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">16\u202fmg<\/span><\/td>\n<td><span class=\"\">3.2\u202fmL<\/span><\/td>\n<td><span class=\"\">5\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">16\u202fmg<\/span><\/td>\n<td><span class=\"\">0.8\u202fmL<\/span><\/td>\n<td><span class=\"\">20\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p class=\"ds-markdown-paragraph\"><em><span class=\"\">Adjust diluent volume based on your experimental requirements. For cell culture applications, typical working concentrations may range from\u00a0<\/span><strong><span class=\"\">0.1\u201110\u202f\u00b5M<\/span><\/strong><span class=\"\">.<\/span><\/em><\/p>\n<h2><span class=\"\">Storage &amp; Stability Guidelines<\/span><\/h2>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Storage Condition<\/span><\/th>\n<th><span class=\"\">Shelf Life<\/span><\/th>\n<th><span class=\"\">Notes<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">Lyophilised at \u201320\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">2 years<\/span><\/td>\n<td><span class=\"\">Use desiccant, protect from light<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Lyophilised at 2\u20118\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">6\u201112 months<\/span><\/td>\n<td><span class=\"\">\u201320\u00b0C storage is strongly preferred for long\u2011term stability<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted at 2\u20118\u00b0C<\/span><\/td>\n<td><span class=\"\">Short\u2011term use<\/span><\/td>\n<td><span class=\"\">Use within days to weeks<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted aliquots at \u201320\u00b0C<\/span><\/td>\n<td><span class=\"\">Up to 3 months<\/span><\/td>\n<td><span class=\"\">Single freeze only; discard after thawing<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2><span class=\"\">Why Choose Wuhan Top Miracle Peptides for ARA-290 (16mg)?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As an authentic licensed peptide supplier based in the\u00a0<\/span><strong><span class=\"\">United Kingdom<\/span><\/strong><span class=\"\">, we supply\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0and a wide range of research\u2011grade compounds under rigorous quality assurance protocols, fully aligned with Google&#8217;s\u00a0<\/span><strong><span class=\"\">E\u2011E\u2011A\u2011T<\/span><\/strong><span class=\"\">\u00a0standards (Experience, Expertise, Authoritativeness, Trustworthiness).<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Verified Purity:<\/span><\/strong><span class=\"\">\u00a0Independent HPLC analysis with purity guaranteed\u00a0<\/span><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0for every batch<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">GMP\u2011Compliant Manufacturing:<\/span><\/strong><span class=\"\">\u00a0All peptides are synthesised under strict quality control conditions.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Full Traceability:<\/span><\/strong><span class=\"\">\u00a0Batch\u2011specific Certificates of Analysis (COA) are available for every order.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Wholesale Supply:<\/span><\/strong><span class=\"\">\u00a0We serve research institutions, laboratories, and wholesale buyers across the UK, EU, and USA with flexible volume pricing and reliable logistics.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">UK\u2011Based Regulatory Compliance:<\/span><\/strong><span class=\"\">\u00a0All products are supplied strictly as research\u2011grade chemicals for laboratory use only (RUO).<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Researchers across the United Kingdom\u2014including those at leading institutions in London, Cambridge, Oxford, Manchester, and Edinburgh\u2014trust us for fast domestic delivery, transparent documentation and professional technical support.<\/span><\/p>\n<h2><span class=\"\">FAQ: ARA-290 (16mg) Research Peptide<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is ARA-290 (16mg) research peptide?<\/span><\/strong><br \/>\n<span class=\"\">ARA-290 (cibinetide) is a synthetic 11\u2011amino\u2011acid peptide engineered from the helix\u2011B surface domain of erythropoietin. It is designed to bind selectively to the innate repair receptor (IRR) \u2014 a heterodimer of EPOR and CD131 \u2014 to mediate tissue\u2011protective and anti\u2011inflammatory effects without erythropoiesis<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the sequence and molecular weight of ARA-290?<\/span><\/strong><br \/>\n<span class=\"\">The sequence is\u00a0<\/span><strong><span class=\"\">{Glp}\u2011Glu\u2011Gln\u2011Leu\u2011Glu\u2011Arg\u2011Ala\u2011Leu\u2011Asn\u2011Ser\u2011Ser<\/span><\/strong><span class=\"\">\u00a0({Glp}\u2011EQLERALNSS). Its molecular formula is C\u2085\u2081H\u2088\u2084N\u2081\u2086O\u2082\u2081, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">1257.31 g\/mol<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What are the primary research applications for ARA-290?<\/span><\/strong><br \/>\n<span class=\"\">ARA-290 is used in neuroprotection and ischaemic research (cerebral stroke, neuropathic pain), inflammation and immune modulation research, metabolic and diabetes research, tissue repair and regenerative research, and frailty and healthspan research<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the mechanism of action of ARA-290?<\/span><\/strong><br \/>\n<span class=\"\">ARA-290 binds selectively to the innate repair receptor (IRR) \u2014 a heterodimer of EPOR and CD131 \u2014 activating the tissue\u2011protective and anti\u2011inflammatory arm of the EPO signalling system without stimulating red blood cell production<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How does ARA-290 differ from erythropoietin?<\/span><\/strong><br \/>\n<span class=\"\">Unlike full\u2011length EPO, which drives erythropoiesis through the classical homodimeric EPOR, ARA-290 selectively engages the heterodimeric IRR to mediate tissue protection without erythropoiesis<\/span><span class=\"\">. It has a plasma half\u2011life of approximately 2 minutes but activates sustained protective effects<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What purity does your ARA-290 (16mg) meet?<\/span><\/strong><br \/>\n<span class=\"\">Our ARA-290 is tested to\u00a0<\/span><strong><span class=\"\">\u226598% purity<\/span><\/strong><span class=\"\">\u00a0by HPLC. A Certificate of Analysis (COA) is supplied with every order<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I reconstitute ARA-290 (16mg)?<\/span><\/strong><br \/>\n<span class=\"\">Reconstitute with sterile bacteriostatic water or sterile PBS (pH\u202f5\u20117). Allow the vial to reach room temperature, then slowly inject the diluent against the inner glass wall and swirl gently. Do not shake. A typical starting concentration is\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I store reconstituted ARA-290?<\/span><\/strong><br \/>\n<span class=\"\">Reconstituted ARA-290 should be stored at 2\u20118\u00b0C for short\u2011term use. For longer storage, aliquot immediately into single\u2011use vials and store at \u201320\u00b0C for up to 3 months. Avoid repeated freeze\u2011thaw cycles.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Is ARA-290 research peptide legal to purchase in the UK?<\/span><\/strong><br \/>\n<span class=\"\">Yes. ARA-290 is a laboratory reagent sold for\u00a0<\/span><strong><span class=\"\">research use only (RUO)<\/span><\/strong><span class=\"\">. It is fully legal to purchase, possess, and use in the United Kingdom for legitimate in\u2011vitro or in\u2011vivo scientific research, provided it is not marketed with therapeutic claims.\u00a0<\/span><strong><span class=\"\">Note:<\/span><\/strong><span class=\"\">\u00a0As of April 2026, Araim Pharmaceuticals, the company that developed ARA-290, has closed operations, and no active IND or NDA exists<\/span><span class=\"\">. The compound is\u00a0<\/span><strong><span class=\"\">not FDA\u2011approved<\/span><\/strong><span class=\"\">\u00a0for human use<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Does Wuhan Top Miracle Peptides ship internationally?<\/span><\/strong><br \/>\n<span class=\"\">Yes. We ship across the EU (France, Germany, Spain, Sweden, Italy) and to the USA from our UK warehouse. Wholesale pricing is available for bulk orders.<\/span><\/p>\n<h2>Wholesale ARA-290 16mg Supply Across the UK and Europe<\/h2>\n<p class=\"isSelectedEnd\">Wuhan Top Miracle Peptides supports wholesale peptide buyers in the United Kingdom and international markets.<\/p>\n<h3>We Support Enquiries From:<\/h3>\n<ul data-spread=\"false\">\n<li>United Kingdom<\/li>\n<li>France<\/li>\n<li>Germany<\/li>\n<li>Spain<\/li>\n<li>Sweden<\/li>\n<li>Italy<\/li>\n<li>USA<\/li>\n<li>Wider Europe<\/li>\n<\/ul>\n<p class=\"isSelectedEnd\">For larger ARA-290 16mg enquiries, contact our team before ordering. This helps confirm stock, documentation, shipping options, product identity, and buyer verification requirements.<\/p>\n<h2>Where to Source ARA-290 16mg in the UK<\/h2>\n<p class=\"isSelectedEnd\">If you are searching for <strong>where to source ARA-290 16mg in the UK<\/strong>, Wuhan Top Miracle Peptides provides a simple professional enquiry process.<\/p>\n<h3>Professional Enquiry Process<\/h3>\n<ol start=\"1\" data-spread=\"false\">\n<li>Review the ARA-290 16mg product details.<\/li>\n<li>Check the current label and batch information.<\/li>\n<li>Confirm whether the batch is listed as ARA-290, ARA290, Cibinetide, pHBSP, or another verified identity.<\/li>\n<li>Ask about COA and purity-related documentation.<\/li>\n<li>Confirm the sequence and salt form where required.<\/li>\n<li>Confirm your shipping country.<\/li>\n<li>Discuss wholesale quantity requirements.<\/li>\n<li>Complete buyer verification where required.<\/li>\n<li>Place a professional enquiry with support from our team.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/bulk-orders\/\"><strong>Bulk Peptides Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shipping-returns\/\"><strong>Shipping &amp; Returns Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/contact-us\/\"><strong>Contact Us Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shop-3\/\"><strong>Shop Page<\/strong><\/a><br \/>\n<strong>Quality \/ Compliance Page<\/strong><br \/>\n<strong>SS-31 Product Page<\/strong><br \/>\n<strong>Humanin Product Page<\/strong><br \/>\n<strong>PubChem \/ compound reference source<\/strong><br \/>\n<strong>Scientific or peptide reference source<\/strong><br \/>\n<strong>GOV.UK \/ MHRA<\/strong><br \/>\n<strong>Google Search Central<\/strong><br \/>\n<code dir=\"ltr\"><\/code><strong>ASA \/ CAP Code Section 12<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">From its origin as an engineered fragment of the helix\u2011B domain of erythropoietin to its well\u2011characterised role as a selective agonist of the innate repair receptor,\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0provides a precisely defined and mechanistically distinct platform for advanced neuroprotection, inflammation, and tissue repair research.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\"> Its ability to engage the tissue\u2011protective arm of the EPO signalling system without erythropoiesis \u2014 supported by peer\u2011reviewed research published in\u00a0<\/span><em><span class=\"\">PNAS<\/span><\/em><span class=\"\">,\u00a0<\/span><em><span class=\"\">Science<\/span><\/em><span class=\"\">, and other authoritative journals \u2014 makes it a valuable addition to any laboratory investigating neuroprotection, inflammatory signalling, or tissue regeneration<\/span><span class=\"\">. By choosing high\u2011purity, lab\u2011verified\u00a0<\/span><strong><span class=\"\">ARA-290 (16mg) research peptide<\/span><\/strong><span class=\"\">\u00a0from\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, you ensure that your research is built on a foundation of quality, reproducibility, and scientific integrity.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Ready to advance your research with ARA-290 (16mg)?<\/span><\/strong><span class=\"\">\u00a0Browse our product catalogue, request a wholesale quote, or contact our support team today to discuss your laboratory&#8217;s specific needs.\u00a0<\/span><strong><span class=\"\">Place your order now<\/span><\/strong><span class=\"\">\u00a0and receive GMP\u2011grade ARA-290 delivered directly to your facility in the UK, EU, or USA.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>buy peptides USA, research peptides wholesale, peptide purity testing, lab grade peptides USA, ARA-290 research peptide, peptides supplier USA<\/p>\n","protected":false},"featured_media":1205,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[18],"product_tag":[1331,1332,1328,1324,1322,1319,1317,1316,1329,1321,1318,1320,1323,1326,1330,1325,1315,1327,1333,495,515,499,1334,498,442,496,497],"class_list":["post-848","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","product_tag-ara-290-16mg-uk-documentation-request","product_tag-ara-290-batch-documentation","product_tag-ara-290-before-and-after","product_tag-ara-290-dosage","product_tag-ara-290-for-immune-support","product_tag-ara-290-for-inflammation","product_tag-ara-290-for-neuropathy","product_tag-ara-290-for-pain","product_tag-ara-290-for-personal-use","product_tag-ara-290-for-sarcoidosis","product_tag-ara-290-for-small-fiber-neuropathy","product_tag-ara-290-for-tissue-repair","product_tag-ara-290-injection-guide","product_tag-ara-290-no-prescription","product_tag-ara-290-professional-enquiry","product_tag-ara-290-treatment-uk","product_tag-buy-ara-290-online-uk","product_tag-cheap-ara-290-uk","product_tag-cibinetide-reference-documentation","product_tag-coa-and-batch-review","product_tag-compliance-led-supply-discussion","product_tag-peptide-purity-documentation","product_tag-phbsp-peptide-documentation","product_tag-professional-peptide-enquiry","product_tag-research-peptide-supply-uk","product_tag-verified-buyer-documentation","product_tag-wholesale-peptide-support","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product\/848","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/comments?post=848"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media\/1205"}],"wp:attachment":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media?parent=848"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=848"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=848"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}