{"id":849,"date":"2026-05-25T03:49:50","date_gmt":"2026-05-25T03:49:50","guid":{"rendered":"https:\/\/wuhantopmiraclepeptides.com\/?post_type=product&#038;p=849"},"modified":"2026-06-27T18:25:45","modified_gmt":"2026-06-27T18:25:45","slug":"b7-33-6mg","status":"publish","type":"product","link":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/product\/b7-33-6mg\/","title":{"rendered":"B7-33 (6mg)"},"content":{"rendered":"<h1><span class=\"\">B7-33 (6mg) Research Peptide: A Single\u2011Chain Relaxin Mimetic for Fibrosis, Cardiac &amp; Vascular Studies<\/span><\/h1>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">If your research investigates fibrosis, cardiac remodelling, or vascular dysfunction,\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0offers a precisely defined and mechanistically distinct synthetic tool. B7-33 is a single\u2011chain peptide analogue derived from the B\u2011chain of human relaxin\u20112 (H2 relaxin)<\/span><span class=\"\">. Unlike the complex two\u2011chain, disulfide\u2011rich structure of native relaxin, B7-33 is a linear 27\u2011amino\u2011acid peptide that is far easier and cheaper to produce<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">What makes B7-33 particularly valuable for research is its\u00a0<\/span><strong><span class=\"\">functional selectivity<\/span><\/strong><span class=\"\">. While it binds to the relaxin family peptide receptor 1 (RXFP1)\u2014the cognate receptor for relaxin\u20112\u2014it preferentially activates the pERK pathway over the cAMP pathway<\/span><span class=\"\">. This selective signalling profile is thought to preserve the potent anti\u2011fibrotic, cardioprotective, and vasoprotective effects of relaxin while avoiding pathways that have been associated with tumour\u2011promoting actions<\/span><span class=\"\">. This makes\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0a valuable tool for laboratories investigating fibrosis, cardiac protection, vascular biology, and preeclampsia.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">At\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, we supply high\u2011purity\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0to research institutions and wholesale buyers across the\u00a0<\/span><strong><span class=\"\">United Kingdom, France, Germany, Spain, Sweden, Italy, and the USA<\/span><\/strong><span class=\"\">. Every batch is lyophilised, HPLC\u2011verified to \u226598% purity, and accompanied by a Certificate of Analysis (COA), ensuring your investigations into fibrosis, cardiac remodelling, and vascular biology begin with uncompromising quality.<\/span><\/p>\n<h2><span class=\"\">What Is B7-33 and How Does It Work?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">To fully appreciate the research potential of\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">, it is essential to understand its biochemical design and the precise mechanism by which it exerts its effects.<\/span><\/p>\n<h3><span class=\"\">The 27\u2011Amino\u2011Acid Single\u2011Chain Peptide<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">B7-33 is a synthetic linear peptide composed of 27 amino acids. Its sequence is\u00a0<\/span><strong><span class=\"\">H\u2011Val\u2011Ile\u2011Lys\u2011Leu\u2011Ser\u2011Gly\u2011Arg\u2011Glu\u2011Leu\u2011Val\u2011Arg\u2011Ala\u2011Gln\u2011Ile\u2011Ala\u2011Ile\u2011Ser\u2011Gly\u2011Met\u2011Ser\u2011Thr\u2011Trp\u2011Ser\u2011Lys\u2011Arg\u2011Ser\u2011Leu\u2011OH<\/span><\/strong><span class=\"\">. Its molecular formula is\u00a0<\/span><strong><span class=\"\">C\u2081\u2083\u2081H\u2082\u2082\u2088N\u2084\u2080O\u2083\u2087S<\/span><\/strong><span class=\"\">, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">2987.52 g\/mol<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The peptide consists of residues 7\u201129 of the B\u2011chain of H2 relaxin, with the addition of a\u00a0<\/span><strong><span class=\"\">KRSL<\/span><\/strong><span class=\"\">\u00a0sequence from positions 30\u201133 of the B1\u201133 isoform, which dramatically improves solubility<\/span><span class=\"\">. Unlike native relaxin, B7\u201133 is a\u00a0<\/span><strong><span class=\"\">single\u2011chain linear peptide<\/span><\/strong><span class=\"\">\u00a0without the complex disulfide\u2011rich structure of the native hormone<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">Mechanism of Action: Functional Selectivity at RXFP1<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The biological activity of\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is mediated through its selective activation of the relaxin family peptide receptor 1 (RXFP1):<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">RXFP1 Binding and Functional Selectivity:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 binds to RXFP1\u2014the cognate receptor for relaxin\u20112<\/span><span class=\"\">. However, unlike native relaxin, which strongly activates both the cAMP and pERK pathways, B7\u201133\u00a0<\/span><strong><span class=\"\">preferentially activates the pERK pathway over cAMP<\/span><\/strong><span class=\"\">. This makes B7\u201133 the first functionally selective agonist of the complex GPCR RXFP1<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Anti\u2011Fibrotic Signalling via RXFP1\u2011AT\u2082R Heterodimers:<\/span><\/strong><span class=\"\">\u00a0The strong anti\u2011fibrotic actions of B7\u201133 involve its activation of\u00a0<\/span><strong><span class=\"\">RXFP1\u2011angiotensin II type 2 receptor (AT\u2082R) heterodimers<\/span><\/strong><span class=\"\">. This induces selective downstream signalling of\u00a0<\/span><strong><span class=\"\">pERK1\/2<\/span><\/strong><span class=\"\">\u00a0and the collagen\u2011degrading enzyme\u00a0<\/span><strong><span class=\"\">matrix metalloproteinase\u20112 (MMP\u20112)<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Inhibition of TGF\u2011\u03b21 Signalling:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 inhibits excessive transforming growth factor \u03b2\u20111 (TGF\u2011\u03b21) signalling, thereby reducing pro\u2011fibrotic effects on myofibroblast differentiation and aberrant extracellular matrix production<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cardioprotection via ERK1\/2\u2011Dependent Pathways:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 confers cardioprotection by attenuating cardiomyocyte death and endoplasmic reticulum stress through ERK1\/2\u2011dependent mechanisms<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Research Note: Avoiding the Tumour\u2011Promoting Pathway<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">A key advantage of B7\u201133 for research is that, in contrast to H2 relaxin,\u00a0<\/span><strong><span class=\"\">B7\u201133 did not promote prostate tumour growth\u00a0<\/span><em><span class=\"\">in vivo<\/span><\/em><span class=\"\">,<\/span><\/strong><span class=\"\">\u00a0likely because it does not strongly activate the cAMP pathway<\/span><span class=\"\">. This functional selectivity allows researchers to study the beneficial anti\u2011fibrotic and cardioprotective effects of relaxin receptor activation without the confounding variable of tumour\u2011promoting signalling.<\/span><\/p>\n<h2><span class=\"\">Key Research Applications for B7-33 (6mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is a versatile tool with applications spanning several domains of biomedical research.<\/span><\/p>\n<h3><span class=\"\">1. Fibrosis &amp; Scarring Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">B7\u201133 has demonstrated potent anti\u2011fibrotic effects in multiple preclinical models. Research applications include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Hypertrophic Scarring:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 modulates fibrotic signalling in human hypertrophic scar fibroblasts, inhibiting excessive TGF\u2011\u03b21 signalling and reducing pro\u2011fibrotic effects<\/span><span class=\"\">. A 2026 study showed that B7\u201133 significantly modulated profibrotic gene expression and downregulated Collagen Type I \u03b1\u20111 Chain (COL1A1)<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Organ Fibrosis:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 has been shown to prevent or reverse organ fibrosis and dysfunction in three pre\u2011clinical rodent models of heart or lung disease<\/span><span class=\"\">. It reversed organ fibrosis in numerous pre\u2011clinical animal studies<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Myocardial Infarction Scarring:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 significantly reduced infarct size (21.99% versus 45.32%;\u00a0<\/span><em><span class=\"\">P<\/span><\/em><span class=\"\">=0.02) and preserved cardiac function in a mouse model of myocardial infarction<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Surgical Mesh Fibrosis:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 is being investigated as an anti\u2011fibrotic coating for surgical meshes to mitigate fibrotic encapsulation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">2. Cardiovascular &amp; Cardiac Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">B7\u201133 has demonstrated significant cardioprotective effects. Research has shown:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cardioprotection Post\u2011Infarction:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 confers acute cardioprotection and limits myocardial infarction\u2011related adverse cardiac remodelling in mice<\/span><span class=\"\">. B7\u201133 significantly reduced infarct size and preserved fractional shortening compared with vehicle<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Reduction of Left Ventricular Fibrosis:<\/span><\/strong><span class=\"\">\u00a0In an isoprenaline\u2011induced cardiomyopathy model, B7\u201133 reduced left ventricular fibrosis and normalised inflammation and cardiomyocyte hypertrophy<\/span><span class=\"\">. B7\u201133 also reduced left ventricular fibrosis more rapidly than the ACE inhibitor perindopril<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Vasoprotection:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 replicates the vasoprotective functions of human relaxin\u20112 (serelaxin), preventing endothelial dysfunction induced by placental trophoblast\u2011conditioned media<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">3. Preeclampsia &amp; Vascular Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">B7\u201133 has been studied for its effects in preeclampsia models:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Preeclampsia Attenuation:<\/span><\/strong><span class=\"\">\u00a0Both B7\u201133 and B7\u201133 fusion proteins demonstrate efficacy in attenuating the symptoms of preeclampsia, including hypertension and inflammation, in the reduced uterine perfusion pressure (RUPP) rat model<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Vascular Function:<\/span><\/strong><span class=\"\">\u00a0B7\u201133 replicates the acute beneficial vascular effects of serelaxin in rat mesenteric arteries<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">4. Drug Delivery &amp; Biomaterial Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">B7\u201133 is being investigated in advanced delivery systems:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Controlled Release Dressings:<\/span><\/strong><span class=\"\">\u00a0Electrospun B7\u201133\u2011loaded dressings enable controlled release over 72 hours, with the peptide retaining antifibrotic activity after incorporation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Biodegradable Coatings:<\/span><\/strong><span class=\"\">\u00a0Poly(lactic\u2011co\u2011glycolic) acid (PLGA) coatings releasing B7\u201133 have been shown to reduce fibrotic encapsulation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"\">Chemical &amp; Physical Specifications<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Accurate characterisation of\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is essential for reproducible experimental design.<\/span><\/p>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Parameter<\/span><\/th>\n<th><span class=\"\">Specification<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong><span class=\"\">Common Names<\/span><\/strong><\/td>\n<td><span class=\"\">B7-33, Relaxin B\u2011chain analogue<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Sequence (One\u2011Letter)<\/span><\/strong><\/td>\n<td><span class=\"\">VIKLSGRELVRAQIAISGMSTWSKRSL<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Sequence (Three\u2011Letter)<\/span><\/strong><\/td>\n<td><span class=\"\">H\u2011Val\u2011Ile\u2011Lys\u2011Leu\u2011Ser\u2011Gly\u2011Arg\u2011Glu\u2011Leu\u2011Val\u2011Arg\u2011Ala\u2011Gln\u2011Ile\u2011Ala\u2011Ile\u2011Ser\u2011Gly\u2011Met\u2011Ser\u2011Thr\u2011Trp\u2011Ser\u2011Lys\u2011Arg\u2011Ser\u2011Leu\u2011OH<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Length (aa)<\/span><\/strong><\/td>\n<td><span class=\"\">27<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Formula<\/span><\/strong><\/td>\n<td><span class=\"\">C\u2081\u2083\u2081H\u2082\u2082\u2088N\u2084\u2080O\u2083\u2087S<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Weight<\/span><\/strong><\/td>\n<td><span class=\"\">~2987.52 g\/mol<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Purity<\/span><\/strong><\/td>\n<td><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0(HPLC verified)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Appearance<\/span><\/strong><\/td>\n<td><span class=\"\">White to off\u2011white lyophilised powder<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Solubility<\/span><\/strong><\/td>\n<td><span class=\"\">Soluble in sterile water and sterile PBS (pH 5\u20117)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Lyophilised)<\/span><\/strong><\/td>\n<td><span class=\"\">\u201320\u00b0C, sealed, protected from light; stable for up to 2 years<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Reconstituted)<\/span><\/strong><\/td>\n<td><span class=\"\">2\u20118\u00b0C for short\u2011term use; single\u2011use aliquots at \u201320\u00b0C for long\u2011term storage<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Note:<\/span><\/strong><span class=\"\">\u00a0The 6\u202fmg mass refers to the weight of the peptide in its lyophilised form. B7\u201133 is a single\u2011chain linear peptide, unlike the complex two\u2011chain, disulfide\u2011rich structure of native relaxin. This structural simplicity is a key advantage for research applications.<\/span><\/p>\n<\/blockquote>\n<h2><span class=\"\">Reconstitution &amp; Handling Protocol for B7-33 (6mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Proper reconstitution of\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is critical for maintaining its structural integrity and biological activity.<\/span><\/p>\n<h3><span class=\"\">Step 1 \u2013 Preparation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Bring the sealed B7\u201133 vial and your chosen diluent (sterile bacteriostatic water or sterile PBS, pH\u202f5\u20117) to room temperature.\u00a0<\/span><em><span class=\"\">Condensation can degrade the lyophilised powder.<\/span><\/em><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Clean your work surface with 70% ethanol and lay out sterile syringes, alcohol wipes and a clean work mat.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 2 \u2013 Vial Sanitisation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Wipe the rubber stopper of the B7\u201133 vial with a fresh 70% ethanol wipe. Allow the alcohol to evaporate completely before piercing.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 3 \u2013 Reconstitution<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Draw your desired volume of diluent into a sterile syringe. A common starting concentration for research applications is\u00a0<\/span><strong><span class=\"\">6\u202fmg per 0.6\u202fmL of diluent<\/span><\/strong><span class=\"\">, yielding a\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">\u00a0stock solution.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Insert the needle and slowly inject the diluent\u00a0<\/span><strong><span class=\"\">against the inner glass wall<\/span><\/strong><span class=\"\">. Do not spray directly onto the lyophilised powder.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Gently swirl the vial until the solution is clear and fully dissolved.\u00a0<\/span><strong><span class=\"\">Do not shake vigorously<\/span><\/strong><span class=\"\">, as shaking can cause denaturation.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 4 \u2013 Aliquoting &amp; Storage<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Immediately after dissolution, aliquot the reconstituted B7\u201133 into single\u2011use sterile vials.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Store aliquots at \u201320\u00b0C.\u00a0<\/span><strong><span class=\"\">Avoid repeated freeze\u2011thaw cycles<\/span><\/strong><span class=\"\">, as peptides are susceptible to degradation.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Once thawed, store at 2\u20118\u00b0C and use within a short period.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Concentration Reference Table<\/span><\/h3>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Vial Mass<\/span><\/th>\n<th><span class=\"\">Diluent Volume<\/span><\/th>\n<th><span class=\"\">Final Concentration<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">6\u202fmg<\/span><\/td>\n<td><span class=\"\">0.6\u202fmL<\/span><\/td>\n<td><span class=\"\">10\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">6\u202fmg<\/span><\/td>\n<td><span class=\"\">1.2\u202fmL<\/span><\/td>\n<td><span class=\"\">5\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">6\u202fmg<\/span><\/td>\n<td><span class=\"\">0.3\u202fmL<\/span><\/td>\n<td><span class=\"\">20\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p class=\"ds-markdown-paragraph\"><em><span class=\"\">Adjust diluent volume based on your experimental requirements. For cell culture applications, typical working concentrations may range from\u00a0<\/span><strong><span class=\"\">0.1\u201110\u202f\u00b5M<\/span><\/strong><span class=\"\">.<\/span><\/em><\/p>\n<h2><span class=\"\">Storage &amp; Stability Guidelines<\/span><\/h2>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Storage Condition<\/span><\/th>\n<th><span class=\"\">Shelf Life<\/span><\/th>\n<th><span class=\"\">Notes<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">Lyophilised at \u201320\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">2 years<\/span><\/td>\n<td><span class=\"\">Use desiccant, protect from light<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Lyophilised at 2\u20118\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">6\u201112 months<\/span><\/td>\n<td><span class=\"\">\u201320\u00b0C storage is strongly preferred for long\u2011term stability<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted at 2\u20118\u00b0C<\/span><\/td>\n<td><span class=\"\">Short\u2011term use<\/span><\/td>\n<td><span class=\"\">Use within days to weeks<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted aliquots at \u201320\u00b0C<\/span><\/td>\n<td><span class=\"\">Up to 3 months<\/span><\/td>\n<td><span class=\"\">Single freeze only; discard after thawing<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2><span class=\"\">Why Choose Wuhan Top Miracle Peptides for B7-33 (6mg)?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As an authentic licensed peptide supplier based in the\u00a0<\/span><strong><span class=\"\">United Kingdom<\/span><\/strong><span class=\"\">, we supply\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0and a wide range of research\u2011grade compounds under rigorous quality assurance protocols, fully aligned with Google&#8217;s\u00a0<\/span><strong><span class=\"\">E\u2011E\u2011A\u2011T<\/span><\/strong><span class=\"\">\u00a0standards (Experience, Expertise, Authoritativeness, Trustworthiness).<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Verified Purity:<\/span><\/strong><span class=\"\">\u00a0Independent HPLC analysis with purity guaranteed\u00a0<\/span><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0for every batch.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">GMP\u2011Compliant Manufacturing:<\/span><\/strong><span class=\"\">\u00a0All peptides are synthesised under strict quality control conditions.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Full Traceability:<\/span><\/strong><span class=\"\">\u00a0Batch\u2011specific Certificates of Analysis (COA) are available for every order.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Wholesale Supply:<\/span><\/strong><span class=\"\">\u00a0We serve research institutions, laboratories, and wholesale buyers across the UK, EU, and USA with flexible volume pricing and reliable logistics.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">UK\u2011Based Regulatory Compliance:<\/span><\/strong><span class=\"\">\u00a0All products are supplied strictly as research\u2011grade chemicals for laboratory use only (RUO).<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Researchers across the United Kingdom\u2014including those at leading institutions in London, Cambridge, Oxford, Manchester, and Edinburgh\u2014trust us for fast domestic delivery, transparent documentation and professional technical support.<\/span><\/p>\n<h2><span class=\"\">FAQ: B7-33 (6mg) Research Peptide<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is B7-33 (6mg) research peptide?<\/span><\/strong><br \/>\n<span class=\"\">B7\u201133 is a synthetic 27\u2011amino\u2011acid single\u2011chain peptide analogue derived from the B\u2011chain of human relaxin\u20112 (H2 relaxin). It is a functionally selective agonist of the relaxin family peptide receptor 1 (RXFP1), preferentially activating the pERK pathway over cAMP<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the sequence and molecular weight of B7-33?<\/span><\/strong><br \/>\n<span class=\"\">The sequence is\u00a0<\/span><strong><span class=\"\">VIKLSGRELVRAQIAISGMSTWSKRSL<\/span><\/strong><span class=\"\">. Its molecular formula is C\u2081\u2083\u2081H\u2082\u2082\u2088N\u2084\u2080O\u2083\u2087S, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">2987.52 g\/mol<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What are the primary research applications for B7-33?<\/span><\/strong><br \/>\n<span class=\"\">B7\u201133 is used in fibrosis and scarring research (hypertrophic scarring, organ fibrosis, myocardial infarction scarring), cardiovascular and cardiac research (cardioprotection, left ventricular fibrosis reduction, vasoprotection), preeclampsia and vascular research, and drug delivery and biomaterial research.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the mechanism of action of B7-33?<\/span><\/strong><br \/>\n<span class=\"\">B7\u201133 binds to RXFP1 and preferentially activates the pERK pathway over cAMP<\/span><span class=\"\">. It activates RXFP1\u2011AT\u2082R heterodimers, inducing pERK1\/2 and MMP\u20112 signalling<\/span><span class=\"\">, inhibits TGF\u2011\u03b21 signalling<\/span><span class=\"\">, and confers cardioprotection via ERK1\/2\u2011dependent mechanisms<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How does B7-33 differ from relaxin-2 in research?<\/span><\/strong><br \/>\n<span class=\"\">Unlike native relaxin, B7\u201133 is a single\u2011chain linear peptide, making it easier and cheaper to produce<\/span><span class=\"\">. It preferentially activates pERK over cAMP, avoiding pathways associated with tumour promotion<\/span><span class=\"\">. Despite this, it retains the anti\u2011fibrotic and cardioprotective effects of relaxin<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What purity does your B7-33 (6mg) meet?<\/span><\/strong><br \/>\n<span class=\"\">Our B7\u201133 is tested to\u00a0<\/span><strong><span class=\"\">\u226598% purity<\/span><\/strong><span class=\"\">\u00a0by HPLC. A Certificate of Analysis (COA) is supplied with every order.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I reconstitute B7-33 (6mg)?<\/span><\/strong><br \/>\n<span class=\"\">Reconstitute with sterile bacteriostatic water or sterile PBS (pH\u202f5\u20117). Allow the vial to reach room temperature, then slowly inject the diluent against the inner glass wall and swirl gently. Do not shake. A typical starting concentration is\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I store reconstituted B7-33?<\/span><\/strong><br \/>\n<span class=\"\">Reconstituted B7\u201133 should be stored at 2\u20118\u00b0C for short\u2011term use. For longer storage, aliquot immediately into single\u2011use vials and store at \u201320\u00b0C for up to 3 months. Avoid repeated freeze\u2011thaw cycles.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Is B7-33 research peptide legal to purchase in the UK?<\/span><\/strong><br \/>\n<span class=\"\">Yes. B7\u201133 is a laboratory reagent sold for\u00a0<\/span><strong><span class=\"\">research use only (RUO)<\/span><\/strong><span class=\"\">. It is fully legal to purchase, possess, and use in the United Kingdom for legitimate in\u2011vitro or in\u2011vivo scientific research, provided it is not marketed with therapeutic claims.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Does Wuhan Top Miracle Peptides ship internationally?<\/span><\/strong><br \/>\n<span class=\"\">Yes. We ship across the EU (France, Germany, Spain, Sweden, Italy) and to the USA from our UK warehouse. Wholesale pricing is available for bulk orders.<\/span><\/p>\n<h2>Wholesale B7-33 6mg Supply Across the UK and Europe<\/h2>\n<p class=\"isSelectedEnd\">Wuhan Top Miracle Peptides supports wholesale peptide buyers in the United Kingdom and international markets.<\/p>\n<h3>We Support Enquiries From:<\/h3>\n<ul data-spread=\"false\">\n<li>United Kingdom<\/li>\n<li>France<\/li>\n<li>Germany<\/li>\n<li>Spain<\/li>\n<li>Sweden<\/li>\n<li>Italy<\/li>\n<li>USA<\/li>\n<li>Wider Europe<\/li>\n<\/ul>\n<p class=\"isSelectedEnd\">For larger B7-33 6mg enquiries, contact our team before ordering. This helps confirm stock, documentation, shipping options, product identity, and buyer verification requirements.<\/p>\n<h2>Where to Source B7-33 6mg in the UK<\/h2>\n<p class=\"isSelectedEnd\">If you are searching for <strong>where to source B7-33 6mg in the UK<\/strong>, Wuhan Top Miracle Peptides provides a simple professional enquiry process.<\/p>\n<h3>Professional Enquiry Process<\/h3>\n<ol start=\"1\" data-spread=\"false\">\n<li>Review the B7-33 6mg product details.<\/li>\n<li>Check the current label and batch information.<\/li>\n<li>Confirm whether the batch is listed as B7-33 or another verified identity.<\/li>\n<li>Ask about COA and purity-related documentation.<\/li>\n<li>Confirm the sequence and salt form where required.<\/li>\n<li>Confirm CAS number and storage notes where required.<\/li>\n<li>Confirm your shipping country.<\/li>\n<li>Discuss wholesale quantity requirements.<\/li>\n<li>Complete buyer verification where required.<\/li>\n<li>Place a professional enquiry with support from our team.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/bulk-orders\/\"><strong>Bulk Peptides Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shipping-returns\/\"><strong>Shipping &amp; Returns Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/contact-us\/\"><strong>Contact Us Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shop-3\/\"><strong>Shop Page<\/strong><\/a><br \/>\n<strong>Quality \/ Compliance Page<\/strong><br \/>\n<strong>ARA-290 Product Page<\/strong><br \/>\n<strong>BPC-157 Product Page<\/strong><br \/>\n<strong>PubChem \/ compound reference source<\/strong><br \/>\n<strong>Scientific or peptide reference source<\/strong><br \/>\n<strong>GOV.UK \/ MHRA<\/strong><br \/>\n<strong>Google Search Central<\/strong><br \/>\n<strong>ASA \/ CAP Code Section 12<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">From its innovative design as a single\u2011chain relaxin mimetic to its well\u2011characterised role as a functionally selective RXFP1 agonist,\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0provides a precisely defined and mechanistically distinct platform for advanced fibrosis, cardiac, and vascular research.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\"> Its ability to preferentially activate the pERK pathway over cAMP, inhibit TGF\u2011\u03b21 signalling, reduce infarct size, and attenuate left ventricular fibrosis\u2014supported by peer\u2011reviewed research published in\u00a0<\/span><em><span class=\"\">Chemical Science<\/span><\/em><span class=\"\">, the\u00a0<\/span><em><span class=\"\">Journal of the American Heart Association<\/span><\/em><span class=\"\">, and other authoritative journals\u2014makes it a valuable addition to any laboratory investigating fibrosis, cardiac remodelling, vascular dysfunction, or preeclampsia. By choosing high\u2011purity, lab\u2011verified\u00a0<\/span><strong><span class=\"\">B7-33 (6mg) research peptide<\/span><\/strong><span class=\"\">\u00a0from\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, you ensure that your research is built on a foundation of quality, reproducibility, and scientific integrity.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Ready to advance your research with B7-33 (6mg)?<\/span><\/strong><span class=\"\">\u00a0Browse our product catalogue, request a wholesale quote, or contact our support team today to discuss your laboratory&#8217;s specific needs.\u00a0<\/span><strong><span class=\"\">Place your order now<\/span><\/strong><span class=\"\">\u00a0and receive GMP\u2011grade B7\u201133 delivered directly to your facility in the UK, EU, or USA.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>lab grade peptides USA, research peptides wholesale, peptide purity testing, buy peptides USA, peptide supplier USA, B7-33 research peptide<\/p>\n","protected":false},"featured_media":1207,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[18],"product_tag":[19,20,21,1337,1344,1345,1336,1338,1343,1335,22,268,23,395,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,857,232,212,50,637,266,1339,1340,215,1342,51,1341,52,53,54,55,56,269,57,218,239],"class_list":["post-849","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","product_tag-alastin","product_tag-alastinskincare-serum","product_tag-antioxidants","product_tag-b7-33-6mg-peptide","product_tag-b7-33-batch-documentation","product_tag-b7-33-peptide-coa-uk","product_tag-b7-33-peptide-uk","product_tag-b7-33-research-peptide","product_tag-b7-33-supplier-uk","product_tag-b7-33-uk","product_tag-bodybuilding","product_tag-coa-peptide-supplier-uk","product_tag-esthetician","product_tag-europe-peptide-supplier","product_tag-ghrp","product_tag-hcgchica","product_tag-hcgcommunity-hcgresults","product_tag-hcgdiet","product_tag-hcgdrop","product_tag-hcgfamily","product_tag-hcginjections-doral","product_tag-hcgjourney","product_tag-hcglife","product_tag-hcgpellets","product_tag-hcgphase","product_tag-hcgplus","product_tag-hcgprotocol","product_tag-hcgsupport","product_tag-hcgusers","product_tag-hcgweightloss","product_tag-hcgworks","product_tag-health","product_tag-hrt","product_tag-hyaluronicacid","product_tag-injectionshcg","product_tag-lipo","product_tag-lipotropic","product_tag-lipotropicinjections","product_tag-miami","product_tag-miamibeach","product_tag-peptide-documentation-uk","product_tag-peptide-purity-uk","product_tag-peptides-for-sale-uk","product_tag-peptideskincare","product_tag-professional-peptide-enquiry-uk","product_tag-professional-peptide-supplier-uk","product_tag-relaxin-peptide-uk","product_tag-relaxin-2-fragment-peptide","product_tag-research-peptides-europe","product_tag-research-grade-b7-33","product_tag-retinol","product_tag-rxfp1-peptide-research","product_tag-sarms","product_tag-skincareroutine","product_tag-supplements","product_tag-testosterone","product_tag-trihextechnology","product_tag-uk-peptide-supplier","product_tag-vitaminc","product_tag-where-to-buy-peptides-in-uk","product_tag-wholesale-peptides-uk","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product\/849","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/comments?post=849"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media\/1207"}],"wp:attachment":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media?parent=849"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=849"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=849"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=849"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}