{"id":855,"date":"2026-05-25T03:49:50","date_gmt":"2026-05-25T03:49:50","guid":{"rendered":"https:\/\/wuhantopmiraclepeptides.com\/?post_type=product&p=855"},"modified":"2026-08-05T23:16:21","modified_gmt":"2026-08-05T23:16:21","slug":"cardiogen-20mg","status":"publish","type":"product","link":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/product\/cardiogen-20mg\/","title":{"rendered":"Cardiogen (20mg)"},"content":{"rendered":"

Cardiogen (20mg) Research Peptide: An AEDR Tetrapeptide for Cardiac & Cellular Repair Studies<\/span><\/h1>\n

If your research investigates cardiac tissue regeneration, fibroblast regulation, or the molecular mechanisms of cellular repair and apoptosis,\u00a0<\/span>Cardiogen (20mg) research peptide<\/span><\/strong>\u00a0\u2014 also known as the AEDR tetrapeptide (Ala\u2011Glu\u2011Asp\u2011Arg) \u2014 offers a precisely defined synthetic tool. Belonging to the Khavinson family of peptide bioregulators, Cardiogen is a short, biologically active tetrapeptide developed from heart tissue-derived polypeptide complexes<\/span>. <\/span><\/p>\n

It is classified as a cardiovascular bioregulator peptide and is investigated in preclinical settings for its potential effects on cardiac tissues, fibroblasts, cellular repair mechanisms and apoptosis regulation<\/span>. Research suggests that Cardiogen may stimulate cardiac cell proliferation, inhibit fibroblast-driven scar formation, and reduce apoptosis by suppressing p53 protein expression<\/span>. This makes\u00a0<\/span>Cardiogen (20mg) research peptide<\/span><\/strong>\u00a0a valuable tool for laboratories investigating cardiovascular biology, tissue regeneration, fibroblast signalling, and the molecular pathways underlying heart function and repair.<\/span><\/p>\n

At\u00a0<\/span>Wuhan Top Miracle Peptides<\/span><\/strong>, we supply high\u2011purity\u00a0<\/span>Cardiogen (20mg) research peptide<\/span><\/strong>\u00a0to research institutions and wholesale buyers across the\u00a0<\/span>United Kingdom, France, Germany, Spain, Sweden, Italy, and the USA<\/span><\/strong>. Every batch is lyophilised, HPLC\u2011verified to \u226598% purity, and accompanied by a Certificate of Analysis (COA), ensuring your investigations into cardiac biology, fibroblast regulation, and cellular repair begin with uncompromising quality.<\/span><\/p>\n

What Is Cardiogen and How Does It Work?<\/span><\/h2>\n

To fully appreciate the research potential of\u00a0<\/span>Cardiogen (20mg) research peptide<\/span><\/strong>, it is essential to understand its biochemical identity and the mechanisms by which it exerts its effects.<\/span><\/p>\n

The AEDR Tetrapeptide<\/span><\/h3>\n

Cardiogen is a synthetic tetrapeptide consisting of four amino acids: alanine, glutamic acid, aspartic acid, and arginine \u2014 the sequence\u00a0<\/span>Ala\u2011Glu\u2011Asp\u2011Arg (AEDR)<\/span><\/strong>. Its molecular formula is\u00a0<\/span>C\u2081\u2088H\u2083\u2081N\u2087O\u2089<\/span><\/strong>, with a molecular weight of approximately\u00a0<\/span>489.5 g\/mol<\/span><\/strong>. It has a PubChem CID of\u00a0<\/span>11583989<\/span><\/strong>. The peptide belongs to the Khavinson family of short peptide bioregulators \u2014 molecules hypothesised to interact with chromatin and DNA to modulate gene expression in a tissue\u2011specific manner<\/span>.<\/span><\/p>\n

Mechanism of Action: Cardiac Repair, Fibroblast Regulation & Gene Modulation<\/span><\/h3>\n

The biological activity of\u00a0<\/span>Cardiogen (20mg) research peptide<\/span><\/strong>\u00a0is hypothesised to involve several intersecting mechanisms:<\/span><\/p>\n

Cardiomyocyte Proliferation and Cardiac Repair<\/span><\/strong><\/p>\n

Research suggests Cardiogen stimulates cardiac cell proliferation and promotes heart muscle regeneration<\/span>. In heart tissue cultures from rats aged 3 months (young) and 24 months (old), Cardiogen uniquely activated cardiomyocyte proliferation while suppressing apoptosis markers like p53 protein \u2014 effects not observed with individual amino acids<\/span>. Notably, Cardiogen’s performance remained robust across both age groups, maintaining its efficacy even in aged tissue where natural regenerative capacity diminishes<\/span>.<\/span><\/p>\n

Fibroblast Regulation and Scar Formation Inhibition<\/span><\/strong><\/p>\n

Cardiogen targets fibroblasts \u2014 key cells in tissue repair \u2014 and is hypothesised to inhibit fibroblast-driven scar formation<\/span>. It may primarily target fibroblasts, which play a crucial role in the formation of scars and tissue regeneration<\/span>. This dual action \u2014 promoting cardiomyocyte proliferation while reducing fibroblast activity \u2014 may contribute to reduced scar formation and improved cardiac remodelling<\/span>.<\/span><\/p>\n

Apoptosis Regulation and p53 Suppression<\/span><\/strong><\/p>\n

Cardiogen reduces apoptosis by suppressing p53 protein expression<\/span>. The tetrapeptide demonstrated a great stimulating effect on proliferation in myocard tissue cultures from both young and old rats, with an immunohistochemical study demonstrating a decrease of p53 protein expression by Cardiogen action<\/span>. Researchers consider the peptide to be an apoptotic reductant in cardiac cells via possibly decreasing p53 expression<\/span>.<\/span><\/p>\n

DNA Interaction and Gene Expression Modulation<\/span><\/strong><\/p>\n

Cardiogen has been shown to modulate DNA hydrolysis and repair processes<\/span>. It does not bind single\u2011stranded deoxyribooligonucleotides, slightly quenches fluorescence of some double\u2011stranded deoxyribooligonucleotides, and strongly quenches fluorescence of methylated and unmethylated \u03bb phage DNA\u2011ethidium bromide complexes<\/span>. Its ability to inhibit DNA hydrolysis indicates that it can control endonuclease DNA hydrolysis, and this effect may be mediated through interaction with the enzyme rather than direct binding to DNA<\/span>.<\/span><\/p>\n

Key Research Applications for Cardiogen (20mg)<\/span><\/h2>\n

Cardiogen (20mg) research peptide<\/span><\/strong>\u00a0is a versatile tool with applications spanning several domains of biomedical research.<\/span><\/p>\n

1. Cardiac & Cardiovascular Research<\/span><\/h3>\n

As a cardiovascular bioregulator peptide, Cardiogen is a valuable tool for studying heart function and repair. Research applications include:<\/span><\/p>\n