{"id":856,"date":"2026-05-25T03:49:50","date_gmt":"2026-05-25T03:49:50","guid":{"rendered":"https:\/\/wuhantopmiraclepeptides.com\/?post_type=product&#038;p=856"},"modified":"2026-07-04T19:22:20","modified_gmt":"2026-07-04T19:22:20","slug":"cagrilintide-5mg-10mg","status":"publish","type":"product","link":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/product\/cagrilintide-5mg-10mg\/","title":{"rendered":"Cagrilintide (5mg &#038; 10mg)"},"content":{"rendered":"<h1><span class=\"\">Cagrilintide (5mg &amp; 10mg) Research Peptide: A Dual Amylin &amp; Calcitonin Receptor Agonist for Metabolic Studies<\/span><\/h1>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">If your research focuses on satiety signalling, energy balance, or the development of next\u2011generation anti\u2011obesity therapeutics, <strong>Cagrilintide (5mg &amp; 10mg) <\/strong><\/span><strong><span class=\"\">research peptide<\/span><\/strong><span class=\"\">\u00a0offers a precisely defined and mechanistically distinct synthetic tool. Cagrilintide (AM833) is a long\u2011acting, lipidated analogue of the pancreatic hormone amylin, engineered to address a key limitation of native amylin\u2014its short half\u2011life<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\"> As a\u00a0<\/span><strong><span class=\"\">dual amylin and calcitonin receptor agonist (DACRA)<\/span><\/strong><span class=\"\">, it binds non\u2011selectively to amylin receptors (AMY1R, AMY2R, AMY3R) and the calcitonin receptor (CTR), activating Gs\u2011coupled signalling pathways that induce satiety and reduce food intake<\/span><span class=\"\">. This distinct mode of action\u2014separate from GLP\u20111\u2011based therapies\u2014positions <strong>Cagrilintide (5mg &amp; 10mg)<\/strong><\/span><strong><span class=\"\">\u00a0research peptide<\/span><\/strong><span class=\"\">\u00a0as a valuable tool for laboratories investigating metabolic regulation, obesity pathophysiology, and the neural circuits that control feeding behaviour.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">At\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, we supply high\u2011purity <strong>Cagrilintide (5mg &amp; 10mg) <\/strong><\/span><strong><span class=\"\">research peptide<\/span><\/strong><span class=\"\">\u00a0to research institutions and wholesale buyers across the\u00a0<\/span><strong><span class=\"\">United Kingdom, France, Germany, Spain, Sweden, Italy, and the USA<\/span><\/strong><span class=\"\">. Every batch is lyophilised, HPLC\u2011verified to \u226598% purity, and accompanied by a Certificate of Analysis (COA), ensuring your investigations into metabolic regulation, satiety signalling, and obesity research begin with uncompromising quality.<\/span><\/p>\n<h2><span class=\"\">What Is Cagrilintide (5mg &amp; 10mg) and How Does It Work?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">To fully appreciate the research potential of <strong>Cagrilintide (5mg &amp; 10mg)<\/strong><\/span><strong><span class=\"\">\u00a0research peptide<\/span><\/strong><span class=\"\">, it is essential to understand its biochemical design and the precise mechanisms by which it exerts its effects.<\/span><\/p>\n<h3><span class=\"\">The Lipidated Amylin Analogue<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Cagrilintide is a 37\u2011amino\u2011acid linear synthetic peptide conjugated to a\u00a0<\/span><strong><span class=\"\">C20 fatty diacid<\/span><\/strong><span class=\"\">\u00a0through a hydrophilic linker at the lysine residue at position 1<\/span><span class=\"\">. This lipidated structure extends its half\u2011life, enabling once\u2011weekly administration in clinical research<\/span><span class=\"\">. The peptide includes a disulfide bridge between cysteine residues at positions 3 and 8<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">Mechanism of Action: Dual Amylin &amp; Calcitonin Receptor Agonism<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The biological activity of Cagrilintide (5mg &amp; 10mg)<\/span><strong><span class=\"\">\u00a0research peptide<\/span><\/strong><span class=\"\">\u00a0is mediated through its non\u2011selective activation of amylin and calcitonin receptors:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Receptor Binding:<\/span><\/strong><span class=\"\">\u00a0Cagrilintide binds to amylin receptors (AMY1R, AMY2R, AMY3R) and the calcitonin receptor (CTR) with high affinity, exhibiting binding IC\u2085\u2080 values of\u00a0<\/span><strong><span class=\"\">170 pM and 223 pM<\/span><\/strong><span class=\"\">\u00a0for hAMY3R and hCTR, respectively<\/span><span class=\"\">. Its binding mode at the receptor transmembrane bundle level is distinct from other DACRAs<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Gs\u2011Protein Signalling:<\/span><\/strong><span class=\"\">\u00a0Receptor activation stimulates Gs\u2011protein signalling, increasing intracellular cAMP levels<\/span><span class=\"\">. Functional analyses reveal that cagrilintide non\u2011selectively activates Gs signalling pathways through both CTR and AMY1R<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Neural Mediation of Energy Balance:<\/span><\/strong><span class=\"\">\u00a0Cagrilintide exerts its effects on energy balance through the dorsal vagal complex (DVC) of the brainstem. Long\u2011term treatment upregulates\u00a0<\/span><strong><span class=\"\">prolactin\u2011releasing hormone (Prlh)<\/span><\/strong><span class=\"\">\u00a0expression in Calcr\/Prlh neurons of the nucleus of the solitary tract\u2014a conserved mechanism across rodents, macaques, and humans<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Distinct Conformational Dynamics:<\/span><\/strong><span class=\"\">\u00a0Structural studies reveal that cagrilintide has an amylin\u2011like binding mode but induces distinct conformational dynamics at calcitonin\u2011family receptors compared to other peptides, which may contribute to its clinical efficacy<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Research Note: A Non\u2011Incretin Pathway for Obesity Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Unlike GLP\u20111 receptor agonists such as semaglutide and tirzepatide, which target incretin pathways, cagrilintide acts through the amylin system\u2014a pancreatic hormone that induces satiety<\/span><span class=\"\">. This distinct mode of action makes it a valuable tool for studying complementary pathways in metabolic regulation<\/span><span class=\"\">. In clinical trials, co\u2011administration of cagrilintide with semaglutide (CagriSema) has achieved\u00a0<\/span><strong><span class=\"\">22.7% weight loss<\/span><\/strong><span class=\"\">\u00a0over 68 weeks, compared to\u00a0<\/span><strong><span class=\"\">16.1%<\/span><\/strong><span class=\"\">\u00a0for semaglutide alone<\/span><span class=\"\">.<\/span><\/p>\n<h2><span class=\"\">Key Research Applications for Cagrilintide (5mg &amp; 10mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cagrilintide (5mg \/ 10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is a versatile tool with applications spanning several domains of biomedical research.<\/span><\/p>\n<h3><span class=\"\">1. Obesity &amp; Metabolic Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As a potent inducer of weight loss through satiety signalling, cagrilintide is a valuable tool for studying obesity pathophysiology. Research applications include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Satiety Signalling Pathways:<\/span><\/strong><span class=\"\">\u00a0Investigating the neural circuits and molecular mechanisms through which amylin receptor activation reduces food intake.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Energy Balance Studies:<\/span><\/strong><span class=\"\">\u00a0Exploring how cagrilintide modulates energy expenditure and metabolic rate.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Combination Therapies:<\/span><\/strong><span class=\"\">\u00a0Studying the synergistic effects of cagrilintide with GLP\u20111 receptor agonists in preclinical models.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Dose\u2011Response Studies:<\/span><\/strong><span class=\"\">\u00a0Characterising the dose\u2011dependent effects of cagrilintide on food intake and body weight<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">2. Receptor Pharmacology &amp; Signalling Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As a non\u2011selective agonist of amylin and calcitonin receptors, cagrilintide serves as a molecular probe for studying receptor pharmacology:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Receptor Binding Assays:<\/span><\/strong><span class=\"\">\u00a0Characterising the affinity and selectivity of cagrilintide for AMYRs and CTR.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Signal Transduction Studies:<\/span><\/strong><span class=\"\">\u00a0Dissecting the Gs\u2011protein signalling pathways activated by dual receptor engagement.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Structure\u2011Activity Relationship (SAR) Studies:<\/span><\/strong><span class=\"\">\u00a0Investigating how modifications to the cagrilintide sequence affect receptor binding and activity<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cryo\u2011EM Structural Studies:<\/span><\/strong><span class=\"\">\u00a0Using cagrilintide as a tool to elucidate receptor complex structures<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">3. Neuroscience &amp; Brain\u2011Gut Axis Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Cagrilintide&#8217;s effects on the dorsal vagal complex make it a valuable tool for studying the neural control of feeding:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Brainstem Circuitry:<\/span><\/strong><span class=\"\">\u00a0Investigating how cagrilintide modulates neuronal populations in the area postrema and nucleus of the solitary tract<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Prlh Signalling:<\/span><\/strong><span class=\"\">\u00a0Studying the role of prolactin\u2011releasing hormone in mediating the effects of amylin receptor agonists<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cross\u2011Species Conservation:<\/span><\/strong><span class=\"\">\u00a0Exploring conserved neural mechanisms of energy balance regulation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">4. Type 2 Diabetes Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Amylin receptor agonists have demonstrated potential in glycemic control. Research applications include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Prandial Glucagon Suppression:<\/span><\/strong><span class=\"\">\u00a0Investigating how cagrilintide suppresses glucagon release and reduces postprandial hyperglycaemia<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Combination with GLP\u20111 Agonists:<\/span><\/strong><span class=\"\">\u00a0Studying the effects of cagrilintide\u2011semaglutide combinations on glycemic control<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Diabetes\u2011Associated Kidney Complications:<\/span><\/strong><span class=\"\">\u00a0Exploring the potential benefits of cagrilintide in diabetic kidney disease models<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">5. Metabolic Disease Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Cagrilintide is being investigated for its broader metabolic effects:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Fatty Liver Disease:<\/span><\/strong><span class=\"\">\u00a0Studying the potential therapeutic benefits of long\u2011acting AMYR agonists in models of fatty liver disease<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Resistant Hypertension:<\/span><\/strong><span class=\"\">\u00a0Investigating the effects of amylin receptor activation on blood pressure regulation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"\">Chemical &amp; Physical Specifications for Cagrilintide (5mg &amp; 10mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Accurate characterisation of\u00a0<\/span><strong><span class=\"\">Cagrilintide (5mg \/ 10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is essential for reproducible experimental design.<\/span><\/p>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Parameter<\/span><\/th>\n<th><span class=\"\">Specification<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong><span class=\"\">Common Names<\/span><\/strong><\/td>\n<td><span class=\"\">Cagrilintide, AM833, AM\u2011833<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Count<\/span><\/strong><\/td>\n<td><span class=\"\">37 amino acids (linear synthetic peptide)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Modification<\/span><\/strong><\/td>\n<td><span class=\"\">C20 fatty diacid conjugated via hydrophilic linker at Lys1<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Disulfide Bridge<\/span><\/strong><\/td>\n<td><span class=\"\">Cys3\u2011Cys8<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Formula<\/span><\/strong><\/td>\n<td><span class=\"\">C\u2081\u2089\u2084H\u2083\u2081\u2082N\u2085\u2084O\u2085\u2089S\u2082<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Weight<\/span><\/strong><\/td>\n<td><span class=\"\">~4409.01 Da<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">CAS Number<\/span><\/strong><\/td>\n<td><span class=\"\">1415456\u201199\u20113<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Binding IC\u2085\u2080 (hAMY3R)<\/span><\/strong><\/td>\n<td><span class=\"\">170 pM<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Binding IC\u2085\u2080 (hCTR)<\/span><\/strong><\/td>\n<td><span class=\"\">223 pM<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">cAMP EC\u2085\u2080 (hAMY3R)<\/span><\/strong><\/td>\n<td><span class=\"\">348 pM<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">cAMP EC\u2085\u2080 (hCTR)<\/span><\/strong><\/td>\n<td><span class=\"\">287 pM<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Purity<\/span><\/strong><\/td>\n<td><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0(HPLC verified)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Appearance<\/span><\/strong><\/td>\n<td><span class=\"\">White to off\u2011white lyophilised powder<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Solubility<\/span><\/strong><\/td>\n<td><span class=\"\">Soluble in water at up to 100 mg\/mL with ultrasonication<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Lyophilised)<\/span><\/strong><\/td>\n<td><span class=\"\">\u201320\u00b0C (1 year) or \u201380\u00b0C (2 years), sealed, protected from moisture<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Reconstituted)<\/span><\/strong><\/td>\n<td><span class=\"\">\u201320\u00b0C (1 month) or \u201380\u00b0C (6 months), sealed, protected from moisture<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Note:<\/span><\/strong><span class=\"\">\u00a0The 5\u202fmg and 10\u202fmg masses refer to the weight of the peptide in its lyophilised form. Cagrilintide is typically supplied as an acetate salt. The peptide is for research use only. Not for human use<\/span><span class=\"\">.<\/span><\/p>\n<\/blockquote>\n<h2><span class=\"\">Reconstitution &amp; Handling Protocol for Cagrilintide (5mg &amp; 10mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Proper reconstitution of <strong>Cagrilintide (5mg &amp; 10mg)<\/strong><\/span><strong><span class=\"\">\u00a0research peptide<\/span><\/strong><span class=\"\">\u00a0is critical for maintaining its structural integrity and biological activity.<\/span><\/p>\n<h3><span class=\"\">Step 1 \u2013 Preparation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Bring the sealed cagrilintide vial and your chosen diluent (sterile bacteriostatic water or sterile PBS, pH\u202f5\u20117) to room temperature.\u00a0<\/span><em><span class=\"\">Condensation can degrade the lyophilised powder.<\/span><\/em><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Clean your work surface with 70% ethanol and lay out sterile syringes, alcohol wipes and a clean work mat.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 2 \u2013 Vial Sanitisation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Wipe the rubber stopper of the cagrilintide vial with a fresh 70% ethanol wipe. Allow the alcohol to evaporate completely before piercing.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 3 \u2013 Reconstitution<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Draw your desired volume of diluent into a sterile syringe. A common starting concentration for research applications is\u00a0<\/span><strong><span class=\"\">5\u202fmg or 10\u202fmg per 1\u202fmL of diluent<\/span><\/strong><span class=\"\">, yielding a\u00a0<\/span><strong><span class=\"\">5\u201110\u202fmg\/mL<\/span><\/strong><span class=\"\">\u00a0stock solution.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Insert the needle and slowly inject the diluent\u00a0<\/span><strong><span class=\"\">against the inner glass wall<\/span><\/strong><span class=\"\">. Do not spray directly onto the lyophilised powder.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Gently swirl the vial until the solution is clear and fully dissolved. Cagrilintide is soluble in water at up to 100\u202fmg\/mL with ultrasonication<\/span><span class=\"\">.\u00a0<\/span><strong><span class=\"\">Do not shake vigorously<\/span><\/strong><span class=\"\">, as shaking can cause denaturation.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 4 \u2013 Aliquoting &amp; Storage<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Immediately after dissolution, aliquot the reconstituted cagrilintide into single\u2011use sterile vials.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Store aliquots at \u201320\u00b0C for up to 1 month or at \u201380\u00b0C for up to 6 months<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Avoid repeated freeze\u2011thaw cycles<\/span><\/strong><span class=\"\">, as peptides are susceptible to degradation.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Once thawed, store at 2\u20118\u00b0C and use within a short period.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Concentration Reference Table<\/span><\/h3>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Vial Mass<\/span><\/th>\n<th><span class=\"\">Diluent Volume<\/span><\/th>\n<th><span class=\"\">Final Concentration<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">5\u202fmg<\/span><\/td>\n<td><span class=\"\">0.5\u202fmL<\/span><\/td>\n<td><span class=\"\">10\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">5\u202fmg<\/span><\/td>\n<td><span class=\"\">1.0\u202fmL<\/span><\/td>\n<td><span class=\"\">5\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">10\u202fmg<\/span><\/td>\n<td><span class=\"\">1.0\u202fmL<\/span><\/td>\n<td><span class=\"\">10\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">10\u202fmg<\/span><\/td>\n<td><span class=\"\">2.0\u202fmL<\/span><\/td>\n<td><span class=\"\">5\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p class=\"ds-markdown-paragraph\"><em><span class=\"\">Adjust diluent volume based on your experimental requirements. For cell culture applications, typical working concentrations may range from\u00a0<\/span><strong><span class=\"\">0.1\u201110\u202f\u00b5M<\/span><\/strong><span class=\"\">.<\/span><\/em><\/p>\n<h2><span class=\"\">Storage &amp; Stability Guidelines for Cagrilintide (5mg &amp; 10mg)<\/span><\/h2>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Storage Condition<\/span><\/th>\n<th><span class=\"\">Shelf Life<\/span><\/th>\n<th><span class=\"\">Notes<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">Lyophilised at \u201380\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">Up to 2 years<\/span><\/td>\n<td><span class=\"\">Sealed, protected from moisture<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Lyophilised at \u201320\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">Up to 1 year<\/span><\/td>\n<td><span class=\"\">Sealed, protected from moisture<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Lyophilised at 2\u20118\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">6\u201112 months<\/span><\/td>\n<td><span class=\"\">\u201320\u00b0C or \u201380\u00b0C storage is strongly preferred for long\u2011term stability<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted at \u201380\u00b0C<\/span><\/td>\n<td><span class=\"\">Up to 6 months<\/span><\/td>\n<td><span class=\"\">Sealed, protected from moisture<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted at \u201320\u00b0C<\/span><\/td>\n<td><span class=\"\">Up to 1 month<\/span><\/td>\n<td><span class=\"\">Sealed, protected from moisture<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted at 2\u20118\u00b0C<\/span><\/td>\n<td><span class=\"\">Short\u2011term use<\/span><\/td>\n<td><span class=\"\">Use within days to weeks<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2><span class=\"\">Why Choose Wuhan Top Miracle Peptides for Cagrilintide (5mg &amp; 10mg)?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As an authentic licensed peptide supplier based in the\u00a0<\/span><strong><span class=\"\">United Kingdom<\/span><\/strong><span class=\"\">, we supply\u00a0<\/span><strong><span class=\"\">Cagrilintide (5mg \/ 10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0and a wide range of research\u2011grade compounds under rigorous quality assurance protocols, fully aligned with Google&#8217;s\u00a0<\/span><strong><span class=\"\">E\u2011E\u2011A\u2011T<\/span><\/strong><span class=\"\">\u00a0standards (Experience, Expertise, Authoritativeness, Trustworthiness).<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Verified Purity:<\/span><\/strong><span class=\"\">\u00a0Independent HPLC analysis with purity guaranteed\u00a0<\/span><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0for every batch<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">GMP\u2011Compliant Manufacturing:<\/span><\/strong><span class=\"\">\u00a0All peptides are synthesised under strict quality control conditions.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Full Traceability:<\/span><\/strong><span class=\"\">\u00a0Batch\u2011specific Certificates of Analysis (COA) are available for every order.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Wholesale Supply:<\/span><\/strong><span class=\"\">\u00a0We serve research institutions, laboratories, and wholesale buyers across the UK, EU, and USA with flexible volume pricing and reliable logistics.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">UK\u2011Based Regulatory Compliance:<\/span><\/strong><span class=\"\">\u00a0All products are supplied strictly as research\u2011grade chemicals for laboratory use only (RUO).<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Researchers across the United Kingdom\u2014including those at leading institutions in London, Cambridge, Oxford, Manchester, and Edinburgh\u2014trust us for fast domestic delivery, transparent documentation and professional technical support.<\/span><\/p>\n<h2><span class=\"\">FAQ: Cagrilintide (5mg &amp; 10mg) Research Peptide<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is Cagrilintide (5mg &amp; 10mg) research peptide?<\/span><\/strong><br \/>\n<span class=\"\">Cagrilintide (AM833) is a long\u2011acting, lipidated analogue of the pancreatic hormone amylin. It is a dual agonist of amylin receptors (AMY1R, AMY2R, AMY3R) and the calcitonin receptor (CTR), functioning as a DACRA (dual amylin and calcitonin receptor agonist)<\/span><span class=\"\">. It is used in research to study satiety, energy balance, and obesity.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the sequence and molecular weight of Cagrilintide?<\/span><\/strong><br \/>\n<span class=\"\">Cagrilintide is a 37\u2011amino\u2011acid linear synthetic peptide with a disulfide bridge between Cys3 and Cys8<\/span><span class=\"\">. Its molecular formula is C\u2081\u2089\u2084H\u2083\u2081\u2082N\u2085\u2084O\u2085\u2089S\u2082, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">4409.01 Da<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What are the primary research applications for Cagrilintide?<\/span><\/strong><br \/>\n<span class=\"\">Cagrilintide is used in obesity and metabolic research (satiety signalling, energy balance), receptor pharmacology and signalling studies (receptor binding, signal transduction), neuroscience and brain\u2011gut axis research (brainstem circuitry, Prlh signalling), type 2 diabetes research, and metabolic disease research (fatty liver disease, resistant hypertension).<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the mechanism of action of Cagrilintide?<\/span><\/strong><br \/>\n<span class=\"\">Cagrilintide binds non\u2011selectively to amylin receptors (AMY1R, AMY2R, AMY3R) and the calcitonin receptor (CTR) with high affinity (IC\u2085\u2080 of 170 pM and 223 pM respectively)<\/span><span class=\"\">. It activates Gs\u2011protein signalling, increasing intracellular cAMP, and modulates energy balance through neural pathways in the dorsal vagal complex<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What purity does your Cagrilintide (5mg &amp; 10mg) meet?<\/span><\/strong><br \/>\n<span class=\"\">Our Cagrilintide is tested to\u00a0<\/span><strong><span class=\"\">\u226598% purity<\/span><\/strong><span class=\"\">\u00a0by HPLC<\/span><span class=\"\">. A Certificate of Analysis (COA) is supplied with every order.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I reconstitute Cagrilintide (5mg \/ 10mg)?<\/span><\/strong><br \/>\n<span class=\"\">Reconstitute with sterile bacteriostatic water or sterile PBS (pH\u202f5\u20117). Allow the vial to reach room temperature, then slowly inject the diluent against the inner glass wall and swirl gently. Do not shake. Cagrilintide is soluble in water at up to 100\u202fmg\/mL with ultrasonication<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I store reconstituted Cagrilintide?<\/span><\/strong><br \/>\n<span class=\"\">Reconstituted Cagrilintide can be stored at \u201320\u00b0C for up to 1 month or at \u201380\u00b0C for up to 6 months, sealed and protected from moisture<\/span><span class=\"\">. Avoid repeated freeze\u2011thaw cycles.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Is Cagrilintide research peptide legal to purchase in the UK?<\/span><\/strong><br \/>\n<span class=\"\">Yes. Cagrilintide is a laboratory reagent sold for\u00a0<\/span><strong><span class=\"\">research use only (RUO)<\/span><\/strong><span class=\"\">. It is fully legal to purchase, possess, and use in the United Kingdom for legitimate in\u2011vitro or in\u2011vivo scientific research, provided it is not marketed with therapeutic claims.\u00a0<\/span><strong><span class=\"\">Note:<\/span><\/strong><span class=\"\">\u00a0Cagrilintide is not currently FDA\u2011approved as a standalone treatment<\/span><span class=\"\">. A New Drug Application for CagriSema (cagrilintide + semaglutide) was submitted to the FDA in December 2025<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Does Wuhan Top Miracle Peptides ship internationally?<\/span><\/strong><br \/>\n<span class=\"\">Yes. We ship across the EU (France, Germany, Spain, Sweden, Italy) and to the USA from our UK warehouse. Wholesale pricing is available for bulk orders.<\/span><\/p>\n<h2>Wholesale Cagrilintide (5mg &amp; 10mg) Supply Across the UK and Europe<\/h2>\n<p class=\"isSelectedEnd\">Wuhan Top Miracle Peptides supports wholesale peptide buyers in the United Kingdom and international markets.<\/p>\n<h3>We Support Enquiries From:<\/h3>\n<ul data-spread=\"false\">\n<li>United Kingdom<\/li>\n<li>France<\/li>\n<li>Germany<\/li>\n<li>Spain<\/li>\n<li>Sweden<\/li>\n<li>Italy<\/li>\n<li>USA<\/li>\n<li>Wider Europe<\/li>\n<\/ul>\n<p class=\"isSelectedEnd\">For larger Cagrilintide (5mg &amp; 10mg) enquiries, contact our team before ordering. This helps confirm stock, documentation, shipping options, product identity, vial strength, and buyer verification requirements.<\/p>\n<h2>Where to Source Cagrilintide (5mg &amp; 10mg) in the UK<\/h2>\n<p class=\"isSelectedEnd\">If you are searching for <strong>where to source Cagrilintide (5mg &amp; 10mg) in the UK<\/strong>, Wuhan Top Miracle Peptides provides a simple professional enquiry process.<\/p>\n<h3>Professional Enquiry Process<\/h3>\n<ol start=\"1\" data-spread=\"false\">\n<li>Review the Cagrilintide (5mg &amp; 10mg) product details.<\/li>\n<li>Check the current label and batch information.<\/li>\n<li>Confirm whether the batch is listed as Cagrilintide (5mg &amp; 10mg) or another verified identity.<\/li>\n<li>Confirm whether you need the 5mg or 10mg vial option.<\/li>\n<li>Ask about COA and purity-related documentation.<\/li>\n<li>Confirm the sequence and salt form where required.<\/li>\n<li>Confirm storage information and shipping country.<\/li>\n<li>Discuss wholesale quantity requirements.<\/li>\n<li>Complete buyer verification where required.<\/li>\n<li>Place a professional enquiry with support from our team.<\/li>\n<\/ol>\n<p>Cagrilintide (5mg &amp; 10mg)<\/p>\n<p><a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/bulk-orders\/\"><strong>Bulk Peptides Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shipping-returns\/\"><strong>Shipping &amp; Returns Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/contact-us\/\"><strong>Contact Us Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shop-3\/\"><strong>Shop Page<\/strong><\/a><br \/>\n<strong>Quality \/ Compliance Page<\/strong><br \/>\n<strong>Retatrutide Product Page<\/strong><br \/>\n<strong>Semaglutide Product Page<\/strong><br \/>\n<strong>Scientific or compound reference source<\/strong><br \/>\n<strong>GOV.UK \/ MHRA<\/strong><br \/>\n<strong>Google Search Central<\/strong><br \/>\n<code dir=\"ltr\"><\/code><strong>ASA \/ CAP Code Section 12<\/strong><\/p>\n<p>Cagrilintide (5mg &amp; 10mg)<\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">From its design as a lipidated, long\u2011acting amylin analogue to its well\u2011characterised role as a dual agonist of amylin and calcitonin receptors, Cagrilintide (5mg &amp; 10mg) <\/span><strong><span class=\"\">research peptide<\/span><\/strong><span class=\"\">\u00a0provides a precisely defined and mechanistically distinct platform for advanced metabolic research. Its ability to activate Gs\u2011signalling pathways, modulate energy balance through the dorsal vagal complex, and induce significant weight loss through satiety signalling\u2014supported by peer\u2011reviewed research published in\u00a0<\/span><em><span class=\"\">Nature Communications<\/span><\/em><span class=\"\">,\u00a0<\/span><em><span class=\"\">Nature Metabolism<\/span><\/em><span class=\"\">, and other authoritative journals\u2014makes it a valuable addition to any laboratory investigating obesity pathophysiology, satiety signalling, or the neural circuits that control feeding behaviour. <\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">By choosing high\u2011purity, lab\u2011verified\u00a0<\/span><strong><span class=\"\">Cagrilintide (5mg \/ 10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0from\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, you ensure that your research is built on a foundation of quality, reproducibility, and scientific integrity.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Ready to advance your research with Cagrilintide (5mg &amp; 10mg)?<\/span><\/strong><span class=\"\">\u00a0Browse our product catalogue, request a wholesale quote, or contact our support team today to discuss your laboratory&#8217;s specific needs.\u00a0<\/span><strong><span class=\"\">Place your order now<\/span><\/strong><span class=\"\">\u00a0and receive GMP\u2011grade Cagrilintide delivered directly to your facility in the UK, EU, or USA.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<h3>Cagrilintide (5mg &amp; 10mg)<\/h3>\n<p>Buy Cagrilintide (5mg &amp; 10mg) peptides for sale in the USA. High-purity, lab-tested peptides. Fast shipping to the US, Canada, UK &amp; Europe. Order now!<\/p>\n","protected":false},"featured_media":130,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[18],"product_tag":[1454,61,62,63,64,22,65,1452,1451,1456,1457,1450,1453,1455,1449,66,268,67,68,69,70,71,395,72,73,74,75,76,77,78,79,80,81,82,83,84,41,85,86,87,88,89,90,91,92,93,94,857,232,95,96,212,97,98,99,50,100,637,266,101,102,215,1458,103,104,105,106,53,107,54,108,109,269,110,111,218,239,112],"class_list":["post-856","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","product_tag-amylin-analogue-peptide-uk","product_tag-antiaging","product_tag-aod9604","product_tag-beauty","product_tag-biohacking","product_tag-bodybuilding","product_tag-bpc157","product_tag-cagrilintide-10mg-uk","product_tag-cagrilintide-5mg-uk","product_tag-cagrilintide-batch-documentation","product_tag-cagrilintide-peptide-coa-uk","product_tag-cagrilintide-peptide-uk","product_tag-cagrilintide-research-peptide","product_tag-cagrilintide-supplier-uk","product_tag-cagrilintide-uk","product_tag-cleanbeauty","product_tag-coa-peptide-supplier-uk","product_tag-collagen","product_tag-collagenpeptides","product_tag-dipeptide","product_tag-egenerativemedicine","product_tag-epigenetics","product_tag-europe-peptide-supplier","product_tag-explorepage","product_tag-fitfam","product_tag-fitlife","product_tag-fitness","product_tag-fitnessmotivation","product_tag-fitspo","product_tag-fyp","product_tag-gains","product_tag-ghkcu","product_tag-glowingskin","product_tag-gym","product_tag-gymlife","product_tag-healing","product_tag-health","product_tag-healthylifestyle","product_tag-hormonetherapy","product_tag-ipamorelin","product_tag-lipcare","product_tag-longevity","product_tag-medical","product_tag-mitochondrialdisease","product_tag-musclebuilding","product_tag-nad","product_tag-peptide","product_tag-peptide-documentation-uk","product_tag-peptide-purity-uk","product_tag-peptideissafe","product_tag-peptidepower","product_tag-peptides-for-sale-uk","product_tag-peptidescience","product_tag-peptideserum","product_tag-peptidesforacne","product_tag-peptideskincare","product_tag-peptideswork","product_tag-professional-peptide-enquiry-uk","product_tag-professional-peptide-supplier-uk","product_tag-recovery","product_tag-research","product_tag-research-peptides-europe","product_tag-research-grade-cagrilintide","product_tag-retatrutide","product_tag-selfcare","product_tag-sermorelin","product_tag-skincare","product_tag-skincareroutine","product_tag-skinhealth","product_tag-supplements","product_tag-trending","product_tag-tripeptide","product_tag-uk-peptide-supplier","product_tag-weightloss","product_tag-wellness","product_tag-where-to-buy-peptides-in-uk","product_tag-wholesale-peptides-uk","product_tag-workout","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product\/856","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/comments?post=856"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media\/130"}],"wp:attachment":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media?parent=856"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=856"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=856"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=856"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}