{"id":886,"date":"2026-05-25T03:49:58","date_gmt":"2026-05-25T03:49:58","guid":{"rendered":"https:\/\/wuhantopmiraclepeptides.com\/?post_type=product&#038;p=886"},"modified":"2026-06-23T09:21:46","modified_gmt":"2026-06-23T09:21:46","slug":"kisspeptin-10-10mg","status":"publish","type":"product","link":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/product\/kisspeptin-10-10mg\/","title":{"rendered":"Kisspeptin-10 (10mg)"},"content":{"rendered":"<h1><span class=\"\">Kisspeptin-10 (10mg) Research Peptide: A Master Regulator of the HPG Axis &amp; Beyond<\/span><\/h1>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">If your research investigates reproductive endocrinology, neuroendocrine signalling, or the molecular mechanisms of metastasis suppression,\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0offers a precisely defined and extensively validated synthetic tool. Kisspeptin-10 (KP-10, Metastin 45-54) is a decapeptide derived from the product of the KISS1 gene and the endogenous ligand for the Kisspeptin receptor (KISS1, GPR54)<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\"> It has emerged as a master regulator of the hypothalamic-pituitary-gonadal (HPG) axis and, consequently, a critical component in the neuroendocrine control of reproduction<\/span><span class=\"\">. Beyond its role in reproductive biology, Kisspeptin-10 has demonstrated significant potential in bone metabolism research and as a metastasis suppressor in various cancer models<\/span><span class=\"\">. This makes\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0a uniquely versatile tool for laboratories investigating endocrinology, neuroscience, oncology, and bone biology.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">At\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, we supply high\u2011purity\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0to research institutions and wholesale buyers across the\u00a0<\/span><strong><span class=\"\">United Kingdom, France, Germany, Spain, Sweden, Italy, and the USA<\/span><\/strong><span class=\"\">. Every batch is lyophilised, HPLC\u2011verified to \u226598% purity, and accompanied by a Certificate of Analysis (COA), ensuring your investigations into reproductive endocrinology, neuroendocrine signalling, and metastasis suppression begin with uncompromising quality.<\/span><\/p>\n<h2><span class=\"\">What Is Kisspeptin-10 and How Does It Work?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">To fully appreciate the research potential of\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">, it is essential to understand its biochemical structure and the diverse mechanisms by which it exerts its effects.<\/span><\/p>\n<h3><span class=\"\">The Decapeptide Derived from KISS1<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Kisspeptin-10 is a synthetic decapeptide corresponding to the C\u2011terminal amino acids 45-54 of the Kisspeptin precursor protein (metastin). Its sequence is\u00a0<\/span><strong><span class=\"\">Tyr\u2011Asn\u2011Trp\u2011Asn\u2011Ser\u2011Phe\u2011Gly\u2011Leu\u2011Arg\u2011Phe\u2011NH\u2082 (YNWNSFGLRF-NH\u2082)<\/span><\/strong><span class=\"\">. The peptide has a molecular formula of\u00a0<\/span><strong><span class=\"\">C\u2086\u2083H\u2088\u2083N\u2081\u2087O\u2081\u2084<\/span><\/strong><span class=\"\">\u00a0and a molecular weight of approximately\u00a0<\/span><strong><span class=\"\">1302.5 Da<\/span><\/strong><span class=\"\">. It has a CAS number of\u00a0<\/span><strong><span class=\"\">374675-21-5<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The peptide is the minimal sequence needed to activate GPR54 signalling<\/span><span class=\"\">\u00a0and shares similar affinities and functions with the longer kisspeptin isoforms<\/span><span class=\"\">. The C\u2011terminal amidation is essential for its biological activity<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">Mechanism of Action: GPR54 Agonism and Downstream Signalling<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The biological activity of\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is mediated through its potent and selective activation of the Kisspeptin receptor (KISS1, GPR54):<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">High\u2011Affinity Receptor Binding:<\/span><\/strong><span class=\"\">\u00a0Kisspeptin-10 binds with high affinity to rat and human KISS1 receptors, with Ki values of\u00a0<\/span><strong><span class=\"\">1.59 nM and 2.33 nM<\/span><\/strong><span class=\"\">, respectively<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">HPG Axis Regulation:<\/span><\/strong><span class=\"\">\u00a0Activation of GPR54 in the hypothalamus stimulates the release of luteinising hormone\u2011releasing hormone (LHRH) from hypothalamic explants<\/span><span class=\"\">. This, in turn, drives the secretion of luteinising hormone (LH) and follicle\u2011stimulating hormone (FSH) from the pituitary, leading to increased gonadal steroidogenesis<\/span><span class=\"\">. Mutations in the Kiss1 receptor are known to cause hypogonadotropic hypogonadism in humans and mice<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Direct Pituitary Effects:<\/span><\/strong><span class=\"\">\u00a0Kisspeptins also exert direct effects on the pituitary, activating gonadotrophs and somatotrophs and stimulating the secretion of LH and growth hormone<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Bone Metabolism:<\/span><\/strong><span class=\"\">\u00a0GPR54 activation by Kisspeptin-10 in osteoclasts causes Dusp18 to dephosphorylate Src at Tyr 416, a pathway that suppresses osteoclast activity and prevents bone loss<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Metastasis Suppression:<\/span><\/strong><span class=\"\">\u00a0The KISS1 gene was originally discovered as a metastasis suppressor gene<\/span><span class=\"\">. Kisspeptin-10 inhibits tumour angiogenesis by suppressing Sp1\u2011mediated VEGF expression and FAK\/Rho GTPase activation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"\">Key Research Applications for Kisspeptin-10 (10mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is a versatile tool with applications spanning several domains of biomedical research.<\/span><\/p>\n<h3><span class=\"\">1. Reproductive Endocrinology &amp; HPG Axis Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As the master regulator of the HPG axis, Kisspeptin-10 is an essential tool for studying the neuroendocrine control of reproduction. Research applications include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Puberty and Fertility:<\/span><\/strong><span class=\"\">\u00a0Investigating the role of the kisspeptin\/GPR54 system in the onset of puberty and the regulation of fertility<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">GnRH Neuroendocrine System:<\/span><\/strong><span class=\"\">\u00a0Studying how Kisspeptin-10 stimulates GnRH release through the Kiss1 receptor<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Gonadotropin Regulation:<\/span><\/strong><span class=\"\">\u00a0Exploring the dose\u2011dependent effects of Kisspeptin-10 on plasma LH, FSH, and testosterone<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Reproductive Disorders:<\/span><\/strong><span class=\"\">\u00a0Investigating potential therapeutic applications for infertility, amenorrhea, and pubertal delay<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">2. Bone Metabolism &amp; Osteoclast Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Kisspeptin-10 has emerged as a critical regulator of bone homeostasis. Research has demonstrated:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Osteoclast Activity Suppression:<\/span><\/strong><span class=\"\">\u00a0Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18\u2011mediated dephosphorylation of Src<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Therapeutic Target:<\/span><\/strong><span class=\"\">\u00a0The Kp\u201110\/Gpr54 axis is a promising therapeutic target to abrogate bone resorption<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Age\u2011Related Bone Loss:<\/span><\/strong><span class=\"\">\u00a0Investigating how Kisspeptin-10 signalling may counteract the over\u2011activation of osteoclasts observed with aging<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">3. Oncology &amp; Metastasis Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The KISS1 gene was first discovered as a metastasis suppressor gene<\/span><span class=\"\">. Kisspeptin-10 is a valuable tool for cancer research:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Metastasis Suppression:<\/span><\/strong><span class=\"\">\u00a0Kisspeptin-10 inhibits metastasis and invasion in mouse melanomas<\/span><span class=\"\">\u00a0and other cancers including gastric, pancreatic, ovarian, and prostate cancer<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Tumour Angiogenesis Inhibition:<\/span><\/strong><span class=\"\">\u00a0Kisspeptin-10 inhibits angiogenesis by suppressing Sp1\u2011mediated VEGF expression and FAK\/Rho GTPase activation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Triple\u2011Negative Breast Cancer:<\/span><\/strong><span class=\"\">\u00a0Exogenous Kisspeptin-10 treatment shows pleiotropic effects, including metastasis suppression and promotion of apoptosis<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Diagnostic Imaging:<\/span><\/strong><span class=\"\">\u00a0Radionuclide\u2011labelled kisspeptin peptides provide a potential target for diagnostic imaging and potentially pan\u2011tumour therapeutic radiopharmaceuticals<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">4. Neuroendocrinology &amp; Behavioural Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Emerging research has explored Kisspeptin-10&#8217;s effects beyond the HPG axis:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Antidepressant\u2011Like Effects:<\/span><\/strong><span class=\"\">\u00a0The antidepressant\u2011like effects of Kisspeptin-10 are reversed by a kisspeptin antagonist, suggesting a role in mood regulation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cerebral Aneurysm Prevention:<\/span><\/strong><span class=\"\">\u00a0The Kisspeptin\u201110\/GPR54 signalling pathway is dysregulated in individuals with cerebral aneurysms, and KP\u201110 administration prevents their formation in mouse models<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"\">Chemical &amp; Physical Specifications<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Accurate characterisation of\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is essential for reproducible experimental design.<\/span><\/p>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Parameter<\/span><\/th>\n<th><span class=\"\">Specification<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong><span class=\"\">Common Names<\/span><\/strong><\/td>\n<td><span class=\"\">Kisspeptin-10, KP-10, Metastin (45-54), Kp-10<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Sequence (One\u2011Letter)<\/span><\/strong><\/td>\n<td><span class=\"\">YNWNSFGLRF-NH\u2082<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Sequence (Three\u2011Letter)<\/span><\/strong><\/td>\n<td><span class=\"\">Tyr\u2011Asn\u2011Trp\u2011Asn\u2011Ser\u2011Phe\u2011Gly\u2011Leu\u2011Arg\u2011Phe\u2011NH\u2082<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Formula<\/span><\/strong><\/td>\n<td><span class=\"\">C\u2086\u2083H\u2088\u2083N\u2081\u2087O\u2081\u2084<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Weight<\/span><\/strong><\/td>\n<td><span class=\"\">~1302.5 Da<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">CAS Number<\/span><\/strong><\/td>\n<td><span class=\"\">374675-21-5<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">PubChem ID<\/span><\/strong><\/td>\n<td><span class=\"\">25240297<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Purity<\/span><\/strong><\/td>\n<td><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0(HPLC verified)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Appearance<\/span><\/strong><\/td>\n<td><span class=\"\">White to off\u2011white lyophilised powder<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Solubility<\/span><\/strong><\/td>\n<td><span class=\"\">Soluble in sterile water (up to 1 mg\/mL) and sterile PBS (pH 5\u20117)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Lyophilised)<\/span><\/strong><\/td>\n<td><span class=\"\">\u201320\u00b0C, sealed, protected from light; stable for up to 2 years<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Reconstituted)<\/span><\/strong><\/td>\n<td><span class=\"\">2\u20118\u00b0C for short\u2011term use; single\u2011use aliquots at \u201320\u00b0C for long\u2011term storage<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Note:<\/span><\/strong><span class=\"\">\u00a0The 10\u202fmg mass refers to the weight of the peptide in its lyophilised form. Kisspeptin-10 is typically supplied as a TFA or acetate salt, which enhances aqueous solubility. The C\u2011terminal amide is essential for biological activity<\/span><span class=\"\">.<\/span><\/p>\n<\/blockquote>\n<h2><span class=\"\">Reconstitution &amp; Handling Protocol for Kisspeptin-10 (10mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Proper reconstitution of\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is critical for maintaining its structural integrity and biological activity. The peptide has a very rapid clearance in vivo, so careful handling is essential<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">Step 1 \u2013 Preparation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Bring the sealed Kisspeptin-10 vial and your chosen diluent (sterile bacteriostatic water or sterile PBS, pH\u202f5\u20117) to room temperature.\u00a0<\/span><em><span class=\"\">Condensation can degrade the lyophilised powder.<\/span><\/em><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Clean your work surface with 70% ethanol and lay out sterile syringes, alcohol wipes and a clean work mat.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 2 \u2013 Vial Sanitisation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Wipe the rubber stopper of the Kisspeptin-10 vial with a fresh 70% ethanol wipe. Allow the alcohol to evaporate completely before piercing.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 3 \u2013 Reconstitution<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Draw your desired volume of diluent into a sterile syringe. A common starting concentration for research applications is\u00a0<\/span><strong><span class=\"\">10\u202fmg per 1\u202fmL of diluent<\/span><\/strong><span class=\"\">, yielding a\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">\u00a0stock solution. Note that the peptide is soluble in water up to 1 mg\/mL<\/span><span class=\"\">; for higher concentrations, gentle sonication may be required.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Insert the needle and slowly inject the diluent\u00a0<\/span><strong><span class=\"\">against the inner glass wall<\/span><\/strong><span class=\"\">. Do not spray directly onto the lyophilised powder.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Gently swirl the vial until the solution is clear and fully dissolved.\u00a0<\/span><strong><span class=\"\">Do not shake vigorously<\/span><\/strong><span class=\"\">, as shaking can cause denaturation.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 4 \u2013 Aliquoting &amp; Storage<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Immediately after dissolution, aliquot the reconstituted Kisspeptin-10 into single\u2011use sterile vials.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Store aliquots at \u201320\u00b0C.\u00a0<\/span><strong><span class=\"\">Avoid repeated freeze\u2011thaw cycles<\/span><\/strong><span class=\"\">, as peptides are susceptible to degradation.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Once thawed, store at 2\u20118\u00b0C and use within a short period.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Concentration Reference Table<\/span><\/h3>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Vial Mass<\/span><\/th>\n<th><span class=\"\">Diluent Volume<\/span><\/th>\n<th><span class=\"\">Final Concentration<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">10\u202fmg<\/span><\/td>\n<td><span class=\"\">1.0\u202fmL<\/span><\/td>\n<td><span class=\"\">10\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">10\u202fmg<\/span><\/td>\n<td><span class=\"\">2.0\u202fmL<\/span><\/td>\n<td><span class=\"\">5\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">10\u202fmg<\/span><\/td>\n<td><span class=\"\">0.5\u202fmL<\/span><\/td>\n<td><span class=\"\">20\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p class=\"ds-markdown-paragraph\"><em><span class=\"\">Adjust diluent volume based on your experimental requirements. For cell culture applications, typical working concentrations range from\u00a0<\/span><strong><span class=\"\">0.1\u201110\u202f\u00b5M<\/span><\/strong><span class=\"\">.<\/span><\/em><\/p>\n<h2><span class=\"\">Storage &amp; Stability Guidelines<\/span><\/h2>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Storage Condition<\/span><\/th>\n<th><span class=\"\">Shelf Life<\/span><\/th>\n<th><span class=\"\">Notes<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">Lyophilised at \u201320\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">2 years<\/span><\/td>\n<td><span class=\"\">Use desiccant, protect from light<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Lyophilised at 2\u20118\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">6\u201112 months<\/span><\/td>\n<td><span class=\"\">\u201320\u00b0C storage is strongly preferred for long\u2011term stability<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted at 2\u20118\u00b0C<\/span><\/td>\n<td><span class=\"\">Short\u2011term use<\/span><\/td>\n<td><span class=\"\">Use within days to weeks<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted aliquots at \u201320\u00b0C<\/span><\/td>\n<td><span class=\"\">Up to 3 months<\/span><\/td>\n<td><span class=\"\">Single freeze only; discard after thawing<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2><span class=\"\">Why Choose Wuhan Top Miracle Peptides for Kisspeptin-10 (10mg)?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As an authentic licensed peptide supplier based in the\u00a0<\/span><strong><span class=\"\">United Kingdom<\/span><\/strong><span class=\"\">, we supply\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0and a wide range of research\u2011grade compounds under rigorous quality assurance protocols, fully aligned with Google&#8217;s\u00a0<\/span><strong><span class=\"\">E\u2011E\u2011A\u2011T<\/span><\/strong><span class=\"\">\u00a0standards (Experience, Expertise, Authoritativeness, Trustworthiness).<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Verified Purity:<\/span><\/strong><span class=\"\">\u00a0Independent HPLC analysis with purity guaranteed\u00a0<\/span><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0for every batch.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">GMP\u2011Compliant Manufacturing:<\/span><\/strong><span class=\"\">\u00a0All peptides are synthesised under strict quality control conditions.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Full Traceability:<\/span><\/strong><span class=\"\">\u00a0Batch\u2011specific Certificates of Analysis (COA) are available for every order.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Wholesale Supply:<\/span><\/strong><span class=\"\">\u00a0We serve research institutions, laboratories, and wholesale buyers across the UK, EU, and USA with flexible volume pricing and reliable logistics.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">UK\u2011Based Regulatory Compliance:<\/span><\/strong><span class=\"\">\u00a0All products are supplied strictly as research\u2011grade chemicals for laboratory use only (RUO).<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Researchers across the United Kingdom\u2014including those at leading institutions in London, Cambridge, Oxford, Manchester, and Edinburgh\u2014trust us for fast domestic delivery, transparent documentation and professional technical support.<\/span><\/p>\n<h2><span class=\"\">FAQ: Kisspeptin-10 (10mg) Research Peptide<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q1: What is Kisspeptin-10 (10mg) research peptide?<\/span><\/strong><br \/>\n<span class=\"\">Kisspeptin-10 (KP-10, Metastin 45-54) is a decapeptide derived from the KISS1 gene product and the endogenous ligand for the Kisspeptin receptor (KISS1, GPR54)<\/span><span class=\"\">. It is a master regulator of the hypothalamic-pituitary-gonadal (HPG) axis and also functions as a metastasis suppressor and regulator of bone metabolism<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q2: What is the sequence and molecular weight of Kisspeptin-10?<\/span><\/strong><br \/>\n<span class=\"\">The sequence is\u00a0<\/span><strong><span class=\"\">Tyr\u2011Asn\u2011Trp\u2011Asn\u2011Ser\u2011Phe\u2011Gly\u2011Leu\u2011Arg\u2011Phe\u2011NH\u2082 (YNWNSFGLRF-NH\u2082)<\/span><\/strong><span class=\"\">. Its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">1302.5 Da<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q3: What are the primary research applications for Kisspeptin-10?<\/span><\/strong><br \/>\n<span class=\"\">Kisspeptin-10 is used in reproductive endocrinology and HPG axis research (puberty, fertility, gonadotropin regulation), bone metabolism and osteoclast studies (preventing bone loss), oncology and metastasis research (suppressing metastasis and angiogenesis), and neuroendocrinology and behavioural research (antidepressant effects, cerebral aneurysm prevention).<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q4: What is the mechanism of action of Kisspeptin-10?<\/span><\/strong><br \/>\n<span class=\"\">Kisspeptin-10 binds with high affinity to the Kisspeptin receptor (GPR54)<\/span><span class=\"\">. This activation stimulates the release of LHRH from the hypothalamus, driving LH and FSH secretion<\/span><span class=\"\">. It also exerts direct pituitary effects<\/span><span class=\"\">, suppresses osteoclast activity via Dusp18\u2011mediated Src dephosphorylation<\/span><span class=\"\">, and inhibits tumour angiogenesis and metastasis<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q5: What purity does your Kisspeptin-10 (10mg) meet?<\/span><\/strong><br \/>\n<span class=\"\">Our Kisspeptin-10 is tested to\u00a0<\/span><strong><span class=\"\">\u226598% purity<\/span><\/strong><span class=\"\">\u00a0by HPLC. A Certificate of Analysis (COA) is supplied with every order.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q6: How should I reconstitute Kisspeptin-10 (10mg)?<\/span><\/strong><br \/>\n<span class=\"\">Reconstitute with sterile bacteriostatic water or sterile PBS (pH\u202f5\u20117). Allow the vial to reach room temperature, then slowly inject the diluent against the inner glass wall and swirl gently. Do not shake. A typical starting concentration is\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q7: How should I store reconstituted Kisspeptin-10?<\/span><\/strong><br \/>\n<span class=\"\">Reconstituted Kisspeptin-10 should be stored at 2\u20118\u00b0C for short\u2011term use. For longer storage, aliquot immediately into single\u2011use vials and store at \u201320\u00b0C for up to 3 months. Avoid repeated freeze\u2011thaw cycles.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q8: Is Kisspeptin-10 research peptide legal to purchase in the UK?<\/span><\/strong><br \/>\n<span class=\"\">Yes. Kisspeptin-10 is a laboratory reagent sold for\u00a0<\/span><strong><span class=\"\">research use only (RUO)<\/span><\/strong><span class=\"\">. It is fully legal to purchase, possess, and use in the United Kingdom for legitimate in\u2011vitro or in\u2011vivo scientific research, provided it is not marketed with therapeutic claims.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Q9: Does Wuhan Top Miracle Peptides ship internationally?<\/span><\/strong><br \/>\n<span class=\"\">Yes. We ship across the EU (France, Germany, Spain, Sweden, Italy) and to the USA from our UK warehouse. Wholesale pricing is available for bulk orders.<\/span><\/p>\n<h2>Wholesale Kisspeptin-10 10mg Supply Across the UK and Europe<\/h2>\n<p class=\"isSelectedEnd\">Wuhan Top Miracle Peptides supports wholesale peptide buyers in the United Kingdom and international markets.<\/p>\n<h3>We Support Enquiries From:<\/h3>\n<ul data-spread=\"false\">\n<li>United Kingdom<\/li>\n<li>France<\/li>\n<li>Germany<\/li>\n<li>Spain<\/li>\n<li>Sweden<\/li>\n<li>Italy<\/li>\n<li>USA<\/li>\n<li>Wider Europe<\/li>\n<\/ul>\n<p class=\"isSelectedEnd\">For larger Kisspeptin-10 10mg enquiries, contact our team before ordering. This helps confirm stock, documentation, shipping options, product identity, and buyer verification requirements.<\/p>\n<h2>Where to Source Kisspeptin-10 10mg in the UK<\/h2>\n<p class=\"isSelectedEnd\">If you are searching for <strong>where to source Kisspeptin-10 10mg in the UK<\/strong>, Wuhan Top Miracle Peptides provides a simple professional enquiry process.<\/p>\n<h3>Professional Enquiry Process<\/h3>\n<ol start=\"1\" data-spread=\"false\">\n<li>Review the Kisspeptin-10 10mg product details.<\/li>\n<li>Check the current label and batch information.<\/li>\n<li>Confirm whether the batch is listed as Kisspeptin-10, Kp-10, or another verified identity.<\/li>\n<li>Ask about COA and purity-related documentation.<\/li>\n<li>Confirm the sequence, amidation status, and salt form where required.<\/li>\n<li>Confirm your shipping country.<\/li>\n<li>Discuss wholesale quantity requirements.<\/li>\n<li>Complete buyer verification where required.<\/li>\n<li>Place a professional enquiry with support from our team.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/bulk-orders\/\"><strong>Bulk Peptides Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shipping-returns\/\"><strong>Shipping &amp; Returns Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/contact-us\/\"><strong>Contact Us Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shop-3\/\"><strong>Shop Page<\/strong><\/a><br \/>\n<strong>Quality \/ Compliance Page<\/strong><br \/>\n<strong>Scientific receptor reference for KISS1R \/ GPR54<\/strong><br \/>\n<strong>Scientific or peer-reviewed reference source<\/strong><br \/>\n<strong>GOV.UK \/ MHRA<\/strong><br \/>\n<strong>Google Search Central<\/strong><br \/>\n<strong>ASA \/ CAP Code Section 12<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">From its discovery as the endogenous ligand for GPR54 to its well\u2011characterised role as a master regulator of the HPG axis, a suppressor of metastasis, and a regulator of bone metabolism,\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0provides a precisely defined and extensively validated platform for advanced endocrinological, oncological, and bone biology research.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\"> Its high\u2011affinity receptor binding (Ki = 1.59 nM for rat, 2.33 nM for human KISS1 receptors), ability to stimulate the HPG axis via LHRH release, and diverse downstream effects\u2014supported by a growing body of peer\u2011reviewed literature published in\u00a0<\/span><em><span class=\"\">Nature Communications<\/span><\/em><span class=\"\">,\u00a0<\/span><em><span class=\"\">Journal of Neuroendocrinology<\/span><\/em><span class=\"\">, and other authoritative journals\u2014makes it a valuable addition to any laboratory investigating reproductive endocrinology, neuroendocrine signalling, metastasis suppression, or bone homeostasis. By choosing high\u2011purity, lab\u2011verified\u00a0<\/span><strong><span class=\"\">Kisspeptin-10 (10mg) research peptide<\/span><\/strong><span class=\"\">\u00a0from\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, you ensure that your research is built on a foundation of quality, reproducibility, and scientific integrity.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Ready to advance your research with Kisspeptin-10 (10mg)?<\/span><\/strong><span class=\"\">\u00a0Browse our product catalogue, request a wholesale quote, or contact our support team today to discuss your laboratory&#8217;s specific needs.\u00a0<\/span><strong><span class=\"\">Place your order now<\/span><\/strong><span class=\"\">\u00a0and receive GMP\u2011grade Kisspeptin-10 delivered directly to your facility in the UK, EU, or USA.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Buy Kisspeptin-10 (10mg) USA. Lab-tested, high-purity peptides shipped across US, Canada, UK &amp; Europe. Wholesale options available.<\/p>\n","protected":false},"featured_media":178,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[18],"product_tag":[1028,1041,268,395,1049,1048,1046,1047,1050,1053,1042,1038,1029,1032,1033,1036,1030,1043,1034,1035,1031,1037,1040,1045,1052,1039,1044,857,232,212,637,266,215,1051,269,218,239],"class_list":["post-886","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","product_tag-buy-kisspeptin-10-online-uk","product_tag-cheap-kisspeptin-10-uk","product_tag-coa-peptide-supplier-uk","product_tag-europe-peptide-supplier","product_tag-gpr54-peptide-research","product_tag-kiss1-peptide-uk","product_tag-kisspeptin-10mg-peptide","product_tag-kisspeptin-peptide-uk","product_tag-kisspeptin-research-peptide","product_tag-kisspeptin-10-batch-documentation","product_tag-kisspeptin-10-before-and-after","product_tag-kisspeptin-10-dosage","product_tag-kisspeptin-10-for-fertility","product_tag-kisspeptin-10-for-hormone-balance","product_tag-kisspeptin-10-for-ivf","product_tag-kisspeptin-10-for-libido","product_tag-kisspeptin-10-for-ovulation","product_tag-kisspeptin-10-for-personal-use","product_tag-kisspeptin-10-for-puberty","product_tag-kisspeptin-10-for-reproductive-health","product_tag-kisspeptin-10-for-testosterone","product_tag-kisspeptin-10-injection-guide","product_tag-kisspeptin-10-no-prescription","product_tag-kisspeptin-10-peptide-uk","product_tag-kisspeptin-10-supplier-uk","product_tag-kisspeptin-10-treatment-uk","product_tag-kisspeptin-10-uk","product_tag-peptide-documentation-uk","product_tag-peptide-purity-uk","product_tag-peptides-for-sale-uk","product_tag-professional-peptide-enquiry-uk","product_tag-professional-peptide-supplier-uk","product_tag-research-peptides-europe","product_tag-research-grade-kisspeptin-10","product_tag-uk-peptide-supplier","product_tag-where-to-buy-peptides-in-uk","product_tag-wholesale-peptides-uk","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product\/886","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/comments?post=886"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media\/178"}],"wp:attachment":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media?parent=886"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=886"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=886"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=886"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}