{"id":887,"date":"2026-05-25T03:49:58","date_gmt":"2026-05-25T03:49:58","guid":{"rendered":"https:\/\/wuhantopmiraclepeptides.com\/?post_type=product&#038;p=887"},"modified":"2026-06-23T09:43:01","modified_gmt":"2026-06-23T09:43:01","slug":"kpv-4mg","status":"publish","type":"product","link":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/product\/kpv-4mg\/","title":{"rendered":"KPV (4mg)"},"content":{"rendered":"<h1><span class=\"\">KPV (4mg) Research Peptide: An Anti-inflammatory Tripeptide for Immune &amp; Wound Healing Studies<\/span><\/h1>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">If your research explores inflammation pathways, immune modulation, or tissue repair,\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0offers a precisely defined and increasingly well\u2011characterised synthetic tool. KPV (Lysine\u2011Proline\u2011Valine) is a tripeptide that represents the C\u2011terminal fragment (amino acids 11\u201113) of alpha\u2011melanocyte\u2011stimulating hormone (\u03b1\u2011MSH)<\/span><span class=\"\">. While \u03b1\u2011MSH is a larger hormone with melanotropic effects that can cause pigmentation, KPV retains the full anti\u2011inflammatory activity of the parent hormone but is free from its melanotropic effects<\/span><span class=\"\">. This makes\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0a valuable tool for laboratories investigating inflammation, immune signalling, wound healing, and antimicrobial resistance.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">At\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, we supply high\u2011purity\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0to research institutions and wholesale buyers across the\u00a0<\/span><strong><span class=\"\">United Kingdom, France, Germany, Spain, Sweden, Italy, and the USA<\/span><\/strong><span class=\"\">. Every batch is lyophilised, HPLC\u2011verified to \u226598% purity, and accompanied by a Certificate of Analysis (COA), ensuring your investigations into inflammation, immune modulation, and tissue repair begin with uncompromising quality.<\/span><\/p>\n<h2><span class=\"\">What Is KPV and How Does It Work?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">To fully appreciate the research potential of\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">, it is essential to understand its biochemical structure and the mechanisms by which it exerts its effects.<\/span><\/p>\n<h3><span class=\"\">The Minimal Bioactive Tripeptide<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">KPV is a synthetic tripeptide with the sequence\u00a0<\/span><strong><span class=\"\">H\u2011Lys\u2011Pro\u2011Val\u2011OH (KPV)<\/span><\/strong><span class=\"\">. Its molecular formula is\u00a0<\/span><strong><span class=\"\">C\u2081\u2086H\u2083\u2080N\u2084O\u2084<\/span><\/strong><span class=\"\">, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">342.43\u2011342.44 g\/mol<\/span><\/strong><span class=\"\">. It has a CAS number of\u00a0<\/span><strong><span class=\"\">67727\u201197\u20113<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The peptide is derived from the C\u2011terminal region of \u03b1\u2011MSH. Unlike the full\u2011length hormone, KPV lacks the sequence motif required for binding to melanocortin receptors (MC\u2011Rs) yet still retains the full anti\u2011inflammatory effect of the parent molecule<\/span><span class=\"\">. It is smaller and more chemically stable than \u03b1\u2011MSH, making it a more robust research tool<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">Mechanism of Action: IL\u20111\u03b2 Inhibition and NF\u2011\u03baB Modulation<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The biological activity of\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is mediated through a distinct mechanism that sets it apart from the full\u2011length \u03b1\u2011MSH hormone:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">IL\u20111\u03b2 Inhibition:<\/span><\/strong><span class=\"\">\u00a0Recent research indicates that KPV is unlikely to mediate its anti\u2011inflammatory effects through melanocortin receptors but is more likely to act through inhibition of IL\u20111\u03b2 functions<\/span><span class=\"\">. This distinguishes it from other \u03b1\u2011MSH\u2011derived peptides<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">NF\u2011\u03baB Signalling Suppression:<\/span><\/strong><span class=\"\">\u00a0KPV suppresses NF\u2011\u03baB signalling, inhibiting the nuclear import of p65RelA<\/span><span class=\"\">. It reduces the activity of nuclear factor kappa\u2011light\u2011chain\u2011enhancer of activated B cells (NF\u2011\u03baB)<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cytokine Modulation:<\/span><\/strong><span class=\"\">\u00a0The peptide decreases pro\u2011inflammatory cytokines such as TNF\u2011\u03b1 and IL\u20116<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Epithelial MC3R Activation:<\/span><\/strong><span class=\"\">\u00a0KPV has been reported to activate epithelial MC3Rs in airway inflammation models<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Research Note: A Unique Anti\u2011Inflammatory Mechanism<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Unlike \u03b1\u2011MSH, which signals through melanocortin receptors and increases cAMP accumulation, KPV does not increase cAMP<\/span><span class=\"\">. Its anti\u2011inflammatory effect is clearly different from that of core MSH peptides<\/span><span class=\"\">. This distinct mechanism makes KPV a valuable tool for dissecting the cellular signalling events that govern inflammatory responses<\/span><span class=\"\">.<\/span><\/p>\n<h2><span class=\"\">Key Research Applications for KPV (4mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is a versatile tool with applications spanning several domains of biomedical research.<\/span><\/p>\n<h3><span class=\"\">1. Inflammation &amp; Immune Modulation Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">KPV is widely utilised in research exploring the molecular mechanisms of inflammation<\/span><span class=\"\">. Research applications include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Cytokine Pathway Studies:<\/span><\/strong><span class=\"\">\u00a0Investigating how KPV modulates pro\u2011inflammatory cytokines including IL\u20111\u03b2, TNF\u2011\u03b1, and IL\u20116<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">NF\u2011\u03baB Signalling:<\/span><\/strong><span class=\"\">\u00a0Studying how KPV suppresses NF\u2011\u03baB activation and nuclear translocation<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Macrophage Activation:<\/span><\/strong><span class=\"\">\u00a0Exploring how KPV modulates macrophage activity and inflammatory responses<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Inflammatory Disease Models:<\/span><\/strong><span class=\"\">\u00a0Investigating KPV&#8217;s potential in inflammatory bowel disease models<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">2. Wound Healing &amp; Tissue Repair Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Recent findings demonstrate that KPV\u2011loaded hydrogels reduce inflammation, promote tissue regeneration, and combat MRSA infections<\/span><span class=\"\">. Research applications include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Corneal Wound Healing:<\/span><\/strong><span class=\"\">\u00a0Studies have shown that KPV facilitates corneal epithelial wound healing in rabbits<\/span><span class=\"\">. In one study, 100% of KPV\u2011treated corneas were completely re\u2011epithelised within 60 hours<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Skin Regeneration:<\/span><\/strong><span class=\"\">\u00a0KPV accelerates wound healing, reduces infection, and promotes the barrier repair of skin or mucosa<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Collagen Synthesis:<\/span><\/strong><span class=\"\">\u00a0The peptide accelerates the synthesis of collagen<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Antimicrobial Activity:<\/span><\/strong><span class=\"\">\u00a0KPV\u2011loaded hydrogels combat MRSA infections<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">3. Gastrointestinal &amp; Inflammatory Bowel Disease Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">KPV has been investigated for its potential in inflammatory bowel disease models:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Colitis Models:<\/span><\/strong><span class=\"\">\u00a0KPV has demonstrated anti\u2011inflammatory effects on colitis in murine models<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Colitis\u2011Associated Cancer:<\/span><\/strong><span class=\"\">\u00a0Studies suggest that KPV may help prevent carcinogenesis in a murine model<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Oral Bioavailability:<\/span><\/strong><span class=\"\">\u00a0The peptide is orally bioavailable<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">4. Antimicrobial &amp; Biofilm Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">KPV exhibits broad\u2011spectrum antimicrobial properties<\/span><span class=\"\">:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">MRSA Infections:<\/span><\/strong><span class=\"\">\u00a0KPV\u2011loaded formulations combat MRSA infections<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Antimicrobial Peptide Research:<\/span><\/strong><span class=\"\">\u00a0The peptide has direct antimicrobial effects against fungi, mould, bacteria, viruses, and parasites<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Biofilm Disruption:<\/span><\/strong><span class=\"\">\u00a0KPV demonstrates antibiofilm properties<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"\">Chemical &amp; Physical Specifications<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Accurate characterisation of\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is essential for reproducible experimental design.<\/span><\/p>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Parameter<\/span><\/th>\n<th><span class=\"\">Specification<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong><span class=\"\">Common Names<\/span><\/strong><\/td>\n<td><span class=\"\">KPV, Lysine\u2011Proline\u2011Valine, \u03b1\u2011MSH (11\u201113)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Sequence (One\u2011Letter)<\/span><\/strong><\/td>\n<td><span class=\"\">KPV<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Sequence (Three\u2011Letter)<\/span><\/strong><\/td>\n<td><span class=\"\">H\u2011Lys\u2011Pro\u2011Val\u2011OH<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Formula<\/span><\/strong><\/td>\n<td><span class=\"\">C\u2081\u2086H\u2083\u2080N\u2084O\u2084<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Weight<\/span><\/strong><\/td>\n<td><span class=\"\">~342.43\u2011342.44 g\/mol<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">CAS Number<\/span><\/strong><\/td>\n<td><span class=\"\">67727\u201197\u20113<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Purity<\/span><\/strong><\/td>\n<td><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0(HPLC verified)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Appearance<\/span><\/strong><\/td>\n<td><span class=\"\">White to off\u2011white lyophilised powder<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Solubility<\/span><\/strong><\/td>\n<td><span class=\"\">Soluble in sterile water and sterile PBS (pH 5\u20117)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Lyophilised)<\/span><\/strong><\/td>\n<td><span class=\"\">\u201320\u00b0C, sealed, protected from light; stable for up to 2 years<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Reconstituted)<\/span><\/strong><\/td>\n<td><span class=\"\">2\u20118\u00b0C for short\u2011term use; single\u2011use aliquots at \u201320\u00b0C for long\u2011term storage<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Note:<\/span><\/strong><span class=\"\">\u00a0The 4\u202fmg mass refers to the weight of the peptide in its lyophilised form. KPV is typically supplied as a TFA or acetate salt, which enhances aqueous solubility<\/span><span class=\"\">. The peptide&#8217;s stability and biological activity have made it a subject of considerable interest in biochemical research<\/span><span class=\"\">.<\/span><\/p>\n<\/blockquote>\n<h2><span class=\"\">Reconstitution &amp; Handling Protocol for KPV (4mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Proper reconstitution of\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is critical for maintaining its structural integrity and biological activity.<\/span><\/p>\n<h3><span class=\"\">Step 1 \u2013 Preparation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Bring the sealed KPV vial and your chosen diluent (sterile bacteriostatic water or sterile PBS, pH\u202f5\u20117) to room temperature.\u00a0<\/span><em><span class=\"\">Condensation can degrade the lyophilised powder.<\/span><\/em><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Clean your work surface with 70% ethanol and lay out sterile syringes, alcohol wipes and a clean work mat.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 2 \u2013 Vial Sanitisation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Wipe the rubber stopper of the KPV vial with a fresh 70% ethanol wipe. Allow the alcohol to evaporate completely before piercing.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 3 \u2013 Reconstitution<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Draw your desired volume of diluent into a sterile syringe. A common starting concentration for research applications is\u00a0<\/span><strong><span class=\"\">4\u202fmg per 0.4\u202fmL of diluent<\/span><\/strong><span class=\"\">, yielding a\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">\u00a0stock solution.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Insert the needle and slowly inject the diluent\u00a0<\/span><strong><span class=\"\">against the inner glass wall<\/span><\/strong><span class=\"\">. Do not spray directly onto the lyophilised powder.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Gently swirl the vial until the solution is clear and fully dissolved.\u00a0<\/span><strong><span class=\"\">Do not shake vigorously<\/span><\/strong><span class=\"\">, as shaking can cause denaturation.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 4 \u2013 Aliquoting &amp; Storage<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Immediately after dissolution, aliquot the reconstituted KPV into single\u2011use sterile vials.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Store aliquots at \u201320\u00b0C.\u00a0<\/span><strong><span class=\"\">Avoid repeated freeze\u2011thaw cycles<\/span><\/strong><span class=\"\">, as peptides are susceptible to degradation.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Once thawed, store at 2\u20118\u00b0C and use within a short period.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Concentration Reference Table<\/span><\/h3>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Vial Mass<\/span><\/th>\n<th><span class=\"\">Diluent Volume<\/span><\/th>\n<th><span class=\"\">Final Concentration<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">4\u202fmg<\/span><\/td>\n<td><span class=\"\">0.4\u202fmL<\/span><\/td>\n<td><span class=\"\">10\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">4\u202fmg<\/span><\/td>\n<td><span class=\"\">0.8\u202fmL<\/span><\/td>\n<td><span class=\"\">5\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">4\u202fmg<\/span><\/td>\n<td><span class=\"\">0.2\u202fmL<\/span><\/td>\n<td><span class=\"\">20\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p class=\"ds-markdown-paragraph\"><em><span class=\"\">Adjust diluent volume based on your experimental requirements. For cell culture applications, typical working concentrations range from\u00a0<\/span><strong><span class=\"\">0.1\u201110\u202f\u00b5M<\/span><\/strong><span class=\"\">.<\/span><\/em><\/p>\n<h2><span class=\"\">Storage &amp; Stability Guidelines<\/span><\/h2>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Storage Condition<\/span><\/th>\n<th><span class=\"\">Shelf Life<\/span><\/th>\n<th><span class=\"\">Notes<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">Lyophilised at \u201320\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">2 years<\/span><\/td>\n<td><span class=\"\">Use desiccant, protect from light<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Lyophilised at 2\u20118\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">6\u201112 months<\/span><\/td>\n<td><span class=\"\">\u201320\u00b0C storage is strongly preferred for long\u2011term stability<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted at 2\u20118\u00b0C<\/span><\/td>\n<td><span class=\"\">Short\u2011term use<\/span><\/td>\n<td><span class=\"\">Use within days to weeks<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted aliquots at \u201320\u00b0C<\/span><\/td>\n<td><span class=\"\">Up to 3 months<\/span><\/td>\n<td><span class=\"\">Single freeze only; discard after thawing<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2><span class=\"\">Why Choose Wuhan Top Miracle Peptides for KPV (4mg)?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As an authentic licensed peptide supplier based in the\u00a0<\/span><strong><span class=\"\">United Kingdom<\/span><\/strong><span class=\"\">, we supply\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0and a wide range of research\u2011grade compounds under rigorous quality assurance protocols, fully aligned with Google&#8217;s\u00a0<\/span><strong><span class=\"\">E\u2011E\u2011A\u2011T<\/span><\/strong><span class=\"\">\u00a0standards (Experience, Expertise, Authoritativeness, Trustworthiness).<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Verified Purity:<\/span><\/strong><span class=\"\">\u00a0Independent HPLC analysis with purity guaranteed\u00a0<\/span><strong><span class=\"\">\u226598%<\/span><\/strong><span class=\"\">\u00a0for every batch.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">GMP\u2011Compliant Manufacturing:<\/span><\/strong><span class=\"\">\u00a0All peptides are synthesised under strict quality control conditions.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Full Traceability:<\/span><\/strong><span class=\"\">\u00a0Batch\u2011specific Certificates of Analysis (COA) are available for every order.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Wholesale Supply:<\/span><\/strong><span class=\"\">\u00a0We serve research institutions, laboratories, and wholesale buyers across the UK, EU, and USA with flexible volume pricing and reliable logistics.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">UK\u2011Based Regulatory Compliance:<\/span><\/strong><span class=\"\">\u00a0All products are supplied strictly as research\u2011grade chemicals for laboratory use only (RUO).<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Researchers across the United Kingdom\u2014including those at leading institutions in London, Cambridge, Oxford, Manchester, and Edinburgh\u2014trust us for fast domestic delivery, transparent documentation and professional technical support.<\/span><\/p>\n<h2><span class=\"\">FAQ: KPV (4mg) Research Peptide<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is KPV (4mg) research peptide?<\/span><\/strong><br \/>\n<span class=\"\">KPV (Lysine\u2011Proline\u2011Valine) is a synthetic tripeptide corresponding to the C\u2011terminal fragment (amino acids 11\u201113) of \u03b1\u2011melanocyte\u2011stimulating hormone (\u03b1\u2011MSH). It retains the full anti\u2011inflammatory activity of \u03b1\u2011MSH but is free from melanotropic effects<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the sequence and molecular weight of KPV?<\/span><\/strong><br \/>\n<span class=\"\">The sequence is\u00a0<\/span><strong><span class=\"\">H\u2011Lys\u2011Pro\u2011Val\u2011OH (KPV)<\/span><\/strong><span class=\"\">. Its molecular formula is C\u2081\u2086H\u2083\u2080N\u2084O\u2084, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">342.43\u2011342.44 g\/mol<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">\u00a0What are the primary research applications for KPV?<\/span><\/strong><br \/>\n<span class=\"\">KPV is used in inflammation and immune modulation research (IL\u20111\u03b2 inhibition, NF\u2011\u03baB suppression), wound healing and tissue repair studies (corneal wound healing, skin regeneration), gastrointestinal and inflammatory bowel disease research, and antimicrobial and biofilm research.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the mechanism of action of KPV?<\/span><\/strong><br \/>\n<span class=\"\">KPV is unlikely to mediate its effects through melanocortin receptors but is more likely to act through inhibition of IL\u20111\u03b2 functions<\/span><span class=\"\">. It suppresses NF\u2011\u03baB signalling, inhibits nuclear import of p65RelA<\/span><span class=\"\">, and decreases pro\u2011inflammatory cytokines such as TNF\u2011\u03b1 and IL\u20116<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">\u00a0How does KPV differ from \u03b1\u2011MSH in research?<\/span><\/strong><br \/>\n<span class=\"\">Unlike \u03b1\u2011MSH, which signals through melanocortin receptors and increases cAMP accumulation, KPV does not increase cAMP<\/span><span class=\"\">. KPV lacks the entire sequence motif required for binding to melanocortin receptors but still retains the full anti\u2011inflammatory effect of \u03b1\u2011MSH<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">\u00a0What purity does your KPV (4mg) meet?<\/span><\/strong><br \/>\n<span class=\"\">Our KPV is tested to\u00a0<\/span><strong><span class=\"\">\u226598% purity<\/span><\/strong><span class=\"\">\u00a0by HPLC. A Certificate of Analysis (COA) is supplied with every order.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I reconstitute KPV (4mg)?<\/span><\/strong><br \/>\n<span class=\"\">Reconstitute with sterile bacteriostatic water or sterile PBS (pH\u202f5\u20117). Allow the vial to reach room temperature, then slowly inject the diluent against the inner glass wall and swirl gently. Do not shake. A typical starting concentration is\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I store reconstituted KPV?<\/span><\/strong><br \/>\n<span class=\"\">Reconstituted KPV should be stored at 2\u20118\u00b0C for short\u2011term use. For longer storage, aliquot immediately into single\u2011use vials and store at \u201320\u00b0C for up to 3 months. Avoid repeated freeze\u2011thaw cycles.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Is KPV research peptide legal to purchase in the UK?<\/span><\/strong><br \/>\n<span class=\"\">Yes. KPV is a laboratory reagent sold for\u00a0<\/span><strong><span class=\"\">research use only (RUO)<\/span><\/strong><span class=\"\">. It is fully legal to purchase, possess, and use in the United Kingdom for legitimate in\u2011vitro or in\u2011vivo scientific research, provided it is not marketed with therapeutic claims.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Does Wuhan Top Miracle Peptides ship internationally?<\/span><\/strong><br \/>\n<span class=\"\">Yes. We ship across the EU (France, Germany, Spain, Sweden, Italy) and to the USA from our UK warehouse. Wholesale pricing is available for bulk orders.<\/span><\/p>\n<h2>Wholesale KPV 4mg Supply Across the UK and Europe<\/h2>\n<p class=\"isSelectedEnd\">Wuhan Top Miracle Peptides supports wholesale peptide buyers in the United Kingdom and international markets.<\/p>\n<h3>We Support Enquiries From:<\/h3>\n<ul data-spread=\"false\">\n<li>United Kingdom<\/li>\n<li>France<\/li>\n<li>Germany<\/li>\n<li>Spain<\/li>\n<li>Sweden<\/li>\n<li>Italy<\/li>\n<li>USA<\/li>\n<li>Wider Europe<\/li>\n<\/ul>\n<p class=\"isSelectedEnd\">For larger KPV 4mg enquiries, contact our team before ordering. This helps confirm stock, documentation, shipping options, product identity, and buyer verification requirements.<\/p>\n<h2>Where to Source KPV 4mg in the UK<\/h2>\n<p class=\"isSelectedEnd\">If you are searching for <strong>where to source KPV 4mg in the UK<\/strong>, Wuhan Top Miracle Peptides provides a simple professional enquiry process.<\/p>\n<h3>Professional Enquiry Process<\/h3>\n<ol start=\"1\" data-spread=\"false\">\n<li>Review the KPV 4mg product details.<\/li>\n<li>Check the current label and batch information.<\/li>\n<li>Confirm whether the batch is listed as KPV, KPV tripeptide, Lys-Pro-Val, or another verified identity.<\/li>\n<li>Ask about COA and purity-related documentation.<\/li>\n<li>Confirm the sequence and salt form where required.<\/li>\n<li>Confirm your shipping country.<\/li>\n<li>Discuss wholesale quantity requirements.<\/li>\n<li>Complete buyer verification where required.<\/li>\n<li>Place a professional enquiry with support from our team.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/bulk-orders\/\"><strong>Bulk Peptides Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shipping-returns\/\"><strong>Shipping &amp; Returns Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/contact-us\/\"><strong>Contact Us Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shop-3\/\"><strong>Shop Page<\/strong><\/a><br \/>\n<strong>Quality \/ Compliance Page<\/strong><br \/>\n<strong>PubChem \/ NCBI reference information<\/strong><br \/>\n<strong>Scientific or peer-reviewed reference source<\/strong><br \/>\n<strong>GOV.UK \/ MHRA<\/strong><br \/>\n<strong>Google Search Central<\/strong><br \/>\n<strong>ASA \/ CAP Code Section 12<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">From its discovery as the minimal bioactive fragment of \u03b1\u2011MSH to its well\u2011characterised role as a potent inhibitor of IL\u20111\u03b2 and NF\u2011\u03baB signalling,\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0provides a precisely defined and increasingly valuable platform for advanced inflammation and immune research. Its ability to modulate pro\u2011inflammatory cytokines, promote wound healing, and combat MRSA infections\u2014supported by peer\u2011reviewed studies published in\u00a0<\/span><em><span class=\"\">PubMed<\/span><\/em><span class=\"\">,\u00a0<\/span><em><span class=\"\">PMC<\/span><\/em><span class=\"\">, and\u00a0<\/span><em><span class=\"\">ScienceDirect<\/span><\/em><span class=\"\">\u2014makes it a valuable addition to any laboratory investigating inflammation pathways, immune modulation, or tissue repair. By choosing high\u2011purity, lab\u2011verified\u00a0<\/span><strong><span class=\"\">KPV (4mg) research peptide<\/span><\/strong><span class=\"\">\u00a0from\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, you ensure that your research is built on a foundation of quality, reproducibility, and scientific integrity.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Ready to advance your research with KPV (4mg)?<\/span><\/strong><span class=\"\">\u00a0Browse our product catalogue, request a wholesale quote, or contact our support team today to discuss your laboratory&#8217;s specific needs.\u00a0<\/span><strong><span class=\"\">Place your order now<\/span><\/strong><span class=\"\">\u00a0and receive GMP\u2011grade KPV delivered directly to your facility in the UK, EU, or USA.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Buy Professional KPV 4mg UK enquiry page. Request COA, batch documentation and compliant wholesale peptide supply support.<\/p>\n","protected":false},"featured_media":179,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[18],"product_tag":[1054,1067,495,515,1071,1072,1068,1064,1062,1056,1061,1057,1060,1055,1069,1058,1059,1063,1066,1070,1065,1073,499,498,442,496,497],"class_list":["post-887","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","product_tag-buy-kpv-online-uk","product_tag-cheap-kpv-uk","product_tag-coa-and-batch-review","product_tag-compliance-led-supply-discussion","product_tag-kpv-4mg-uk-documentation-request","product_tag-kpv-batch-documentation","product_tag-kpv-before-and-after","product_tag-kpv-dosage","product_tag-kpv-for-colitis","product_tag-kpv-for-gut-health","product_tag-kpv-for-ibd","product_tag-kpv-for-immune-support","product_tag-kpv-for-infection","product_tag-kpv-for-inflammation","product_tag-kpv-for-personal-use","product_tag-kpv-for-skin-repair","product_tag-kpv-for-wound-healing","product_tag-kpv-injection-guide","product_tag-kpv-no-prescription","product_tag-kpv-professional-enquiry","product_tag-kpv-treatment-uk","product_tag-lys-pro-val-peptide-reference-documentation","product_tag-peptide-purity-documentation","product_tag-professional-peptide-enquiry","product_tag-research-peptide-supply-uk","product_tag-verified-buyer-documentation","product_tag-wholesale-peptide-support","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product\/887","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/comments?post=887"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media\/179"}],"wp:attachment":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media?parent=887"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=887"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=887"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=887"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}