{"id":919,"date":"2026-05-25T03:50:03","date_gmt":"2026-05-25T03:50:03","guid":{"rendered":"https:\/\/wuhantopmiraclepeptides.com\/?post_type=product&p=919"},"modified":"2026-06-21T07:31:00","modified_gmt":"2026-06-21T07:31:00","slug":"melanotan-2-10mg","status":"publish","type":"product","link":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/product\/melanotan-2-10mg\/","title":{"rendered":"Melanotan 2 (10mg)"},"content":{"rendered":"

Melanotan 2 (10mg) Research Peptide: A Multi\u2011Receptor Melanocortin Agonist for Pigmentation & CNS Studies<\/span><\/h1>\n

If your research explores the pharmacology of melanocortin receptors, the molecular pathways of skin pigmentation, or the complex interplay between metabolic and central nervous system signalling,\u00a0<\/span>Melanotan 2 (10mg) research peptide<\/span><\/strong>\u00a0offers a uniquely versatile and well\u2011characterised synthetic tool. Also known as MT\u2011II, this cyclic heptapeptide (Ac\u2011Nle\u2011cyclo[Asp\u2011His\u2011D\u2011Phe\u2011Arg\u2011Trp\u2011Lys]\u2011NH\u2082) is a potent, non\u2011selective agonist of several melanocortin receptor subtypes\u2014MC1R, MC3R, MC4R, and MC5R<\/span>.<\/span><\/p>\n

Unlike the linear MC1R\u2011selective analogue afamelanotide (Melanotan I), Melanotan II incorporates a lactam bridge between Asp\u2075 and Lys\u00b9\u2070 that restricts conformational flexibility and confers enhanced metabolic stability<\/span>. This structural feature, combined with its ability to cross the blood\u2011brain barrier, makes\u00a0<\/span>Melanotan 2 (10mg) research peptide<\/span><\/strong>\u00a0a valuable tool for laboratories investigating melanogenesis, appetite regulation, sexual behaviour, and metabolic rate.<\/span><\/p>\n

At\u00a0<\/span>Wuhan Top Miracle Peptides<\/span><\/strong>, we supply high\u2011purity\u00a0<\/span>Melanotan 2 (10mg) research peptide<\/span><\/strong>\u00a0to research institutions and wholesale buyers across the\u00a0<\/span>United Kingdom, France, Germany, Spain, Sweden, Italy, and the USA<\/span><\/strong>. Every batch is lyophilised, HPLC\u2011verified to \u226598% purity, and accompanied by a Certificate of Analysis (COA), ensuring your investigations into melanocortin receptor pharmacology, pigmentation, and CNS signalling begin with uncompromising quality.<\/span><\/p>\n

What Is Melanotan 2 and How Does It Work?<\/span><\/h2>\n

To fully appreciate the research potential of\u00a0<\/span>Melanotan 2 (10mg) research peptide<\/span><\/strong>, it is essential to understand its biochemical design and the precise mechanism by which it modulates multiple melanocortin receptor subtypes.<\/span><\/p>\n

The Cyclic Heptapeptide<\/span><\/h3>\n

Melanotan 2 is a synthetic cyclic heptapeptide with the sequence\u00a0<\/span>Ac\u2011Nle\u2011cyclo[Asp\u2011His\u2011D\u2011Phe\u2011Arg\u2011Trp\u2011Lys]\u2011NH\u2082<\/span><\/strong>. Its molecular formula is\u00a0<\/span>C\u2085\u2080H\u2086\u2089N\u2081\u2085O\u2089<\/span><\/strong>, and its molecular weight is approximately\u00a0<\/span>1024.18\u20111024.2 g\/mol<\/span><\/strong>. It has a CAS number of\u00a0<\/span>121062\u201108\u20116<\/span><\/strong>.<\/span><\/p>\n

The peptide incorporates two critical structural features that distinguish it from linear \u03b1\u2011MSH analogues:<\/span><\/p>\n

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    Norleucine (Nle) substitution at the N\u2011terminus<\/span><\/strong>\u00a0(replacing the oxidation\u2011prone methionine)<\/span><\/p>\n<\/li>\n

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    Lactam bridge between Asp\u2075 and Lys\u00b9\u2070<\/span><\/strong>, forming a cyclic structure that restricts conformational flexibility and confers enhanced metabolic stability<\/span><\/p>\n<\/li>\n<\/ul>\n

    These modifications confer resistance to enzymatic degradation and enhance receptor binding affinity, making Melanotan 2 a more stable and potent research tool than the native hormone. The N\u2011terminal acetylation further enhances the peptide’s stability<\/span>.<\/span><\/p>\n

    Mechanism of Action: Multi\u2011Receptor Melanocortin Agonism<\/span><\/h3>\n

    The biological activity of\u00a0<\/span>Melanotan 2 (10mg) research peptide<\/span><\/strong>\u00a0is mediated through its action as a potent, non\u2011selective agonist at multiple melanocortin receptors<\/span>:<\/span><\/p>\n