{"id":955,"date":"2026-05-25T03:50:07","date_gmt":"2026-05-25T03:50:07","guid":{"rendered":"https:\/\/wuhantopmiraclepeptides.com\/?post_type=product&#038;p=955"},"modified":"2026-06-18T06:39:32","modified_gmt":"2026-06-18T06:39:32","slug":"syn-ake-200mg","status":"publish","type":"product","link":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/product\/syn-ake-200mg\/","title":{"rendered":"Syn-AKE (200mg)"},"content":{"rendered":"<h1><span class=\"\">Syn-AKE (200mg) Research Peptide: A Synthetic nAChR Antagonist for Neuromuscular Studies<\/span><\/h1>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">If your research investigates neuromuscular signalling, nicotinic acetylcholine receptor (nAChR) pharmacology, or the molecular mechanisms of muscle contraction,\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0offers a precisely engineered synthetic tool. Also known as Dipeptide Diaminobutyroyl Benzylamide Diacetate or Tripeptide-3, this compound is a biomimetic tripeptide inspired by the venom of the temple viper (<\/span><em><span class=\"\">Tropidolaemus wagleri<\/span><\/em><span class=\"\">)<\/span><span class=\"\">. It mimics the activity of the snake venom peptide waglerin-1, functioning as a reversible antagonist at the muscle nicotinic acetylcholine receptor (mnAChR)<\/span><span class=\"\">. By binding to nAChR subunits and blocking acetylcholine from binding, Syn-AKE reduces neuromuscular excitatory signalling<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">At\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, we supply high\u2011purity\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0to research institutions and wholesale buyers across the\u00a0<\/span><strong><span class=\"\">United Kingdom, France, Germany, Spain, Sweden, Italy, and the USA<\/span><\/strong><span class=\"\">. Every batch is lyophilised, HPLC\u2011verified to \u226599% purity, and accompanied by a Certificate of Analysis (COA), ensuring your investigations into neuromuscular signalling, receptor pharmacology, and formulation science begin with uncompromising quality.<\/span><\/p>\n<h2><span class=\"\">What Is Syn\u2011AKE and How Does It Work?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">To fully appreciate the research potential of\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">, it is essential to understand its biochemical design and the precise mechanism by which it modulates neuromuscular signalling.<\/span><\/p>\n<h3><span class=\"\">The Synthetic Tripeptide<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Syn\u2011AKE is a synthetic tripeptide derivative with the sequence\u00a0<\/span><strong><span class=\"\">\u03b2-Ala-Pro-Dab-NH-Bzl<\/span><\/strong><span class=\"\">\u00a0(beta-alanyl-L-prolyl-3-aminomethyl-L-alanine benzyl amide)<\/span><span class=\"\">. As a diacetate salt, its molecular formula is\u00a0<\/span><strong><span class=\"\">C\u2081\u2089H\u2082\u2089N\u2085O\u2083\u00b72C\u2082H\u2084O\u2082<\/span><\/strong><span class=\"\">, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">495.6 g\/mol<\/span><\/strong><span class=\"\">. It has a CAS number of\u00a0<\/span><strong><span class=\"\">823202-99-9<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The compound is also referred to as Tripeptide-3 and is classified as a synthetic peptide derivative and a novel snake venom-like active compound<\/span><span class=\"\">. Its design is inspired by waglerin-1, a 22\u2011amino\u2011acid peptide found in the venom of the temple viper (<\/span><em><span class=\"\">Tropidolaemus wagleri<\/span><\/em><span class=\"\">)<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">Mechanism of Action: Competitive Antagonism at nAChRs<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The biological activity of\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is rooted in its ability to act as a reversible antagonist at the muscle nicotinic acetylcholine receptor (mnAChR)<\/span><span class=\"\">:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Receptor Binding:<\/span><\/strong><span class=\"\">\u00a0Syn\u2011AKE binds to specific subunits of the nicotinic acetylcholine receptor at the neuromuscular junction, particularly at the interface involving \u03b11 or \u03b5 subunits<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Competitive Inhibition:<\/span><\/strong><span class=\"\">\u00a0By occupying the receptor site, it blocks acetylcholine from binding, thereby preventing the receptor from opening its ion channel<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Reduction of Neuromuscular Signalling:<\/span><\/strong><span class=\"\">\u00a0This antagonism reduces neuromuscular excitatory signalling, leading to a relaxation of muscle contractions<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Reversible Action:<\/span><\/strong><span class=\"\">\u00a0Unlike botulinum toxin, which irreversibly cleaves SNARE proteins, Syn\u2011AKE&#8217;s effect is reversible, making it a more controlled tool for research applications<\/span><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Binding Affinity and Selectivity<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Research indicates that Syn\u2011AKE acts on the postsynaptic membrane as a reversible antagonist of muscle nicotinic acetylcholine receptors<\/span><span class=\"\">. In vitro studies have demonstrated its ability to bind to the SIRT1 receptor with a binding energy of -9.32 kcal\/mol, suggesting stable interactions with key molecular targets<\/span><span class=\"\">.<\/span><\/p>\n<h2><span class=\"\">Key Research Applications for Syn-AKE (200mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is a versatile tool with applications spanning several areas of neuromuscular and formulation research.<\/span><\/p>\n<h3><span class=\"\">Neuromuscular Signalling &amp; nAChR Pharmacology<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The most fundamental application of Syn\u2011AKE lies in its ability to serve as a molecular probe for studying nicotinic acetylcholine receptor function. Its mechanism as a reversible antagonist makes it a valuable tool for:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Investigating the structural and functional properties of muscle nAChRs<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Studying the kinetics of receptor-ligand interactions at the neuromuscular junction<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Exploring the role of specific nAChR subunits in neuromuscular transmission<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Developing and validating models of receptor antagonism<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">In vitro studies have shown that Syn\u2011AKE can reduce muscle contraction frequency by up to\u00a0<\/span><strong><span class=\"\">82% within 1 minute<\/span><\/strong><span class=\"\">\u00a0in certain experimental models<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">\u00a0Topical Formulation &amp; Transdermal Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As a small, synthetic peptide, Syn\u2011AKE is of significant interest in formulation science. Its physicochemical properties make it suitable for:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Studying transdermal peptide delivery systems<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Investigating the stability and bioavailability of topical peptide formulations<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Developing and validating novel delivery vehicles for peptide actives<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Exploring the relationship between peptide structure and skin penetration<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">The compound has been incorporated into various topical vehicles, including creams, serums, and patches, to study formulation variables affecting peptide stability and delivery.<\/span><\/p>\n<h3><span class=\"\">Protein\u2011Protein Interaction &amp; Molecular Recognition Studies<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Beyond its specific role in nAChR pharmacology, Syn\u2011AKE serves as a model system for studying protein\u2011peptide interactions. Research applications include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Investigating how short peptide fragments mimic the activity of larger venom peptides<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Studying the structural requirements for high\u2011affinity binding to nAChRs<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Developing computational models of peptide\u2011receptor interactions<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Exploring the relationship between peptide sequence, conformation, and biological activity<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Computational studies have investigated Syn\u2011AKE&#8217;s interactions with matrix metalloproteinases (MMPs) and Sirtuin 1 (SIRT1)<\/span><span class=\"\">.<\/span><\/p>\n<h3><span class=\"\">Comparative Neuromuscular Research<\/span><\/h3>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Syn\u2011AKE provides a useful comparator for studying different approaches to neuromuscular modulation. Research applications include:<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Comparing the effects of reversible nAChR antagonists with irreversible SNARE inhibitors (e.g., botulinum toxin)<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Studying the differential effects of various nAChR antagonists on muscle contraction<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Investigating the reversibility and recovery of neuromuscular function after peptide exposure<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Exploring the potential for synergistic effects with other neuromodulatory compounds<\/span><\/p>\n<\/li>\n<\/ul>\n<h2><span class=\"\">Chemical &amp; Physical Specifications<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Accurate characterisation of\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is essential for reproducible experimental design. Below are the verified specifications from multiple research suppliers.<\/span><\/p>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Parameter<\/span><\/th>\n<th><span class=\"\">Specification<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong><span class=\"\">Common Names<\/span><\/strong><\/td>\n<td><span class=\"\">Syn\u2011AKE, SYN\u00ae\u2011AKE, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Tripeptide\u20113<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Amino Acid Sequence<\/span><\/strong><\/td>\n<td><span class=\"\">\u03b2\u2011Ala\u2011Pro\u2011Dab\u2011NH\u2011Bzl (beta\u2011alanyl\u2011L\u2011prolyl\u20113\u2011aminomethyl\u2011L\u2011alanine benzyl amide)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Formula<\/span><\/strong><\/td>\n<td><span class=\"\">C\u2081\u2089H\u2082\u2089N\u2085O\u2083\u00b72C\u2082H\u2084O\u2082 (diacetate salt)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Molecular Weight<\/span><\/strong><\/td>\n<td><span class=\"\">~495.6 g\/mol<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">CAS Number<\/span><\/strong><\/td>\n<td><span class=\"\">823202\u201199\u20119<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Purity<\/span><\/strong><\/td>\n<td><strong><span class=\"\">\u226599%<\/span><\/strong><span class=\"\">\u00a0(HPLC verified)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Appearance<\/span><\/strong><\/td>\n<td><span class=\"\">White to off\u2011white lyophilised powder<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Solubility<\/span><\/strong><\/td>\n<td><span class=\"\">Soluble in water and sterile PBS (pH 5\u20117)<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Lyophilised)<\/span><\/strong><\/td>\n<td><span class=\"\">\u201320\u00b0C, sealed, protected from light; stable for up to 2 years<\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span class=\"\">Storage (Reconstituted)<\/span><\/strong><\/td>\n<td><span class=\"\">2\u20118\u00b0C for up to 28 days; single\u2011use aliquots at \u201320\u00b0C for up to 3 months<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<blockquote>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Note:<\/span><\/strong><span class=\"\">\u00a0The 200\u202fmg mass refers to the weight of the peptide in its lyophilised form. Syn\u2011AKE is typically supplied as a diacetate salt, which enhances aqueous solubility.<\/span><\/p>\n<\/blockquote>\n<h2><span class=\"\">Reconstitution &amp; Handling Protocol for Syn-AKE (200mg)<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Proper reconstitution of\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0is critical for maintaining its structural integrity and biological activity.<\/span><\/p>\n<h3><span class=\"\">Step 1 \u2013 Preparation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Bring the sealed Syn\u2011AKE vial and your chosen diluent (sterile bacteriostatic water or sterile PBS, pH\u202f5\u20117) to room temperature.\u00a0<\/span><em><span class=\"\">Condensation can degrade the lyophilised powder.<\/span><\/em><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Clean your work surface with 70% ethanol and lay out sterile syringes, alcohol wipes and a clean work mat.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 2 \u2013 Vial Sanitisation<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Wipe the rubber stopper of the Syn\u2011AKE vial with a fresh 70% ethanol wipe. Allow the alcohol to evaporate completely before piercing.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 3 \u2013 Reconstitution<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Draw your desired volume of diluent into a sterile syringe. A common starting concentration for research applications is\u00a0<\/span><strong><span class=\"\">200\u202fmg per 20\u202fmL of diluent<\/span><\/strong><span class=\"\">, yielding a\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">\u00a0stock solution.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Insert the needle and slowly inject the diluent\u00a0<\/span><strong><span class=\"\">against the inner glass wall<\/span><\/strong><span class=\"\">. Do not spray directly onto the lyophilised powder.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Gently swirl the vial until the solution is clear and fully dissolved.\u00a0<\/span><strong><span class=\"\">Do not shake vigorously<\/span><\/strong><span class=\"\">, as shaking can cause denaturation.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Step 4 \u2013 Aliquoting &amp; Storage<\/span><\/h3>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Immediately after dissolution, aliquot the reconstituted Syn\u2011AKE into single\u2011use sterile vials.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Store aliquots at \u201320\u00b0C. Avoid repeated freeze\u2011thaw cycles.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Once thawed, store at 2\u20118\u00b0C and use within\u00a0<\/span><strong><span class=\"\">28 days<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<\/li>\n<\/ul>\n<h3><span class=\"\">Concentration Reference Table<\/span><\/h3>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Vial Mass<\/span><\/th>\n<th><span class=\"\">Diluent Volume<\/span><\/th>\n<th><span class=\"\">Final Concentration<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">200\u202fmg<\/span><\/td>\n<td><span class=\"\">20\u202fmL<\/span><\/td>\n<td><span class=\"\">10\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">200\u202fmg<\/span><\/td>\n<td><span class=\"\">10\u202fmL<\/span><\/td>\n<td><span class=\"\">20\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">200\u202fmg<\/span><\/td>\n<td><span class=\"\">40\u202fmL<\/span><\/td>\n<td><span class=\"\">5\u202fmg\/mL<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p class=\"ds-markdown-paragraph\"><em><span class=\"\">Adjust diluent volume based on your experimental requirements. Syn\u2011AKE is fully soluble in water at these concentrations.<\/span><\/em><\/p>\n<h2><span class=\"\">Storage &amp; Stability Guidelines<\/span><\/h2>\n<div class=\"ds-scroll-area ds-scroll-area--show-on-focus-within ds-scroll-area--enabled _1210dd7 c03cafe9\">\n<div class=\"ds-scroll-area__gutters\">\n<div class=\"ds-scroll-area__horizontal-gutter\"><\/div>\n<div class=\"ds-scroll-area__vertical-gutter\"><\/div>\n<\/div>\n<table>\n<thead>\n<tr>\n<th><span class=\"\">Storage Condition<\/span><\/th>\n<th><span class=\"\">Shelf Life<\/span><\/th>\n<th><span class=\"\">Notes<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><span class=\"\">Lyophilised at \u201320\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">2 years<\/span><\/td>\n<td><span class=\"\">Use desiccant, protect from light.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Lyophilised at 2\u20118\u00b0C, unopened<\/span><\/td>\n<td><span class=\"\">6\u201112 months<\/span><\/td>\n<td><span class=\"\">\u201320\u00b0C storage is strongly preferred for long\u2011term stability.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted at 2\u20118\u00b0C<\/span><\/td>\n<td><span class=\"\">Up to 28 days<\/span><\/td>\n<td><span class=\"\">Must be sterile; use aseptic technique for each withdrawal.<\/span><\/td>\n<\/tr>\n<tr>\n<td><span class=\"\">Reconstituted aliquots at \u201320\u00b0C<\/span><\/td>\n<td><span class=\"\">Up to 3 months<\/span><\/td>\n<td><span class=\"\">Single freeze only; discard after thawing.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2><span class=\"\">Why Choose Wuhan Top Miracle Peptides for Syn-AKE (200mg)?<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">As an authentic licensed peptide supplier based in the\u00a0<\/span><strong><span class=\"\">United Kingdom<\/span><\/strong><span class=\"\">, we supply\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0and a wide range of research\u2011grade compounds under rigorous quality assurance protocols, fully aligned with Google&#8217;s\u00a0<\/span><strong><span class=\"\">E\u2011E\u2011A\u2011T<\/span><\/strong><span class=\"\">\u00a0standards (Experience, Expertise, Authoritativeness, Trustworthiness).<\/span><\/p>\n<ul>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Verified Purity:<\/span><\/strong><span class=\"\">\u00a0Independent HPLC analysis with purity guaranteed\u00a0<\/span><strong><span class=\"\">\u226599%<\/span><\/strong><span class=\"\">\u00a0for every batch.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">GMP\u2011Compliant Manufacturing:<\/span><\/strong><span class=\"\">\u00a0All peptides are synthesised in ISO\u202f13485:2016 and GMP\u2011certified facilities, ensuring batch\u2011to\u2011batch consistency.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Full Traceability:<\/span><\/strong><span class=\"\">\u00a0Batch\u2011specific Certificates of Analysis (COA) are available for every order.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Wholesale Supply:<\/span><\/strong><span class=\"\">\u00a0We serve research institutions, laboratories, and wholesale buyers across the UK, EU, and USA with flexible volume pricing and reliable logistics.<\/span><\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">UK\u2011Based Regulatory Compliance:<\/span><\/strong><span class=\"\">\u00a0All products are supplied strictly as research\u2011grade chemicals for laboratory use only (RUO).<\/span><\/p>\n<\/li>\n<\/ul>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">Researchers across the United Kingdom\u2014including those at leading institutions in London, Cambridge, Oxford, Manchester, and Edinburgh\u2014trust us for fast domestic delivery, transparent documentation and professional technical support.<\/span><\/p>\n<h2><span class=\"\">FAQ: Syn-AKE (200mg) Research Peptide<\/span><\/h2>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is Syn-AKE (200mg) research peptide?<\/span><\/strong><br \/>\n<span class=\"\">Syn\u2011AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate, Tripeptide\u20113) is a synthetic tripeptide derivative inspired by the venom of the temple viper (<\/span><em><span class=\"\">Tropidolaemus wagleri<\/span><\/em><span class=\"\">). It acts as a reversible antagonist of muscle nicotinic acetylcholine receptors (nAChRs), reducing neuromuscular signalling<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the sequence and molecular weight of Syn\u2011AKE?<\/span><\/strong><br \/>\n<span class=\"\">The sequence is\u00a0<\/span><strong><span class=\"\">\u03b2\u2011Ala\u2011Pro\u2011Dab\u2011NH\u2011Bzl<\/span><\/strong><span class=\"\">\u00a0(beta\u2011alanyl\u2011L\u2011prolyl\u20113\u2011aminomethyl\u2011L\u2011alanine benzyl amide)<\/span><span class=\"\">. Its molecular formula is C\u2081\u2089H\u2082\u2089N\u2085O\u2083\u00b72C\u2082H\u2084O\u2082, and its molecular weight is approximately\u00a0<\/span><strong><span class=\"\">495.6 g\/mol<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What are the primary research applications for Syn\u2011AKE?<\/span><\/strong><br \/>\n<span class=\"\">Syn\u2011AKE is used in neuromuscular signalling and nAChR pharmacology studies, topical formulation and transdermal research, protein\u2011protein interaction investigations, and comparative neuromuscular research.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What is the mechanism of action of Syn\u2011AKE?<\/span><\/strong><br \/>\n<span class=\"\">Syn\u2011AKE acts as a reversible antagonist at the muscle nicotinic acetylcholine receptor (mnAChR). It binds to nAChR subunits, blocking acetylcholine from binding and reducing neuromuscular excitatory signalling<\/span><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">What purity does your Syn-AKE (200mg) meet?<\/span><\/strong><br \/>\n<span class=\"\">Our Syn\u2011AKE is tested to\u00a0<\/span><strong><span class=\"\">\u226599% purity<\/span><\/strong><span class=\"\">\u00a0by HPLC. A Certificate of Analysis (COA) is supplied with every order.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I reconstitute Syn-AKE (200mg)?<\/span><\/strong><br \/>\n<span class=\"\">Reconstitute with sterile bacteriostatic water or sterile PBS (pH\u202f5\u20117). Allow the vial to reach room temperature, then slowly inject the diluent against the inner glass wall and swirl gently. Do not shake. A typical starting concentration is\u00a0<\/span><strong><span class=\"\">10\u202fmg\/mL<\/span><\/strong><span class=\"\">.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">How should I store reconstituted Syn\u2011AKE?<\/span><\/strong><br \/>\n<span class=\"\">Reconstituted Syn\u2011AKE should be stored at 2\u20118\u00b0C and used within 28 days. For longer storage, aliquot immediately into single\u2011use vials and store at \u201320\u00b0C for up to 3 months. Avoid repeated freeze\u2011thaw cycles.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Is Syn-AKE research peptide legal to purchase in the UK?<\/span><\/strong><br \/>\n<span class=\"\">Yes. Syn\u2011AKE is a laboratory reagent sold for\u00a0<\/span><strong><span class=\"\">research use only (RUO)<\/span><\/strong><span class=\"\">. It is fully legal to purchase, possess, and use in the United Kingdom for legitimate in\u2011vitro or in\u2011vivo scientific research, provided it is not marketed with therapeutic claims.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Does Wuhan Top Miracle Peptides ship internationally?<\/span><\/strong><br \/>\n<span class=\"\">Yes. We ship across the EU (France, Germany, Spain, Sweden, Italy) and to the USA from our UK warehouse. Wholesale pricing is available for bulk orders.<\/span><\/p>\n<h2>Wholesale Syn-AKE 200mg Supply Across the UK and Europe<\/h2>\n<p class=\"isSelectedEnd\">Wuhan Top Miracle Peptides supports wholesale peptide and cosmetic ingredient buyers in the United Kingdom and international markets.<\/p>\n<h3>We Support Enquiries From:<\/h3>\n<ul data-spread=\"false\">\n<li>United Kingdom<\/li>\n<li>France<\/li>\n<li>Germany<\/li>\n<li>Spain<\/li>\n<li>Sweden<\/li>\n<li>Italy<\/li>\n<li>USA<\/li>\n<li>Wider Europe<\/li>\n<\/ul>\n<p class=\"isSelectedEnd\">For larger Syn-AKE 200mg enquiries, contact our team before ordering. This helps confirm stock, wholesale pricing, documentation, shipping options, and buyer requirements.<\/p>\n<h2>Where to Buy Syn-AKE 200mg in the UK<\/h2>\n<p class=\"isSelectedEnd\">If you are searching for <strong>where to buy Syn-AKE 200mg in the UK<\/strong>, Wuhan Top Miracle Peptides provides a simple research-focused enquiry process.<\/p>\n<h3>How to Order<\/h3>\n<ol start=\"1\" data-spread=\"false\">\n<li>Review the Syn-AKE 200mg product details.<\/li>\n<li>Check the current label and batch information.<\/li>\n<li>Confirm the INCI name or product identity from documentation.<\/li>\n<li>Contact our team for availability.<\/li>\n<li>Ask about COA and purity-related documentation.<\/li>\n<li>Confirm your shipping country.<\/li>\n<li>Discuss wholesale quantity requirements.<\/li>\n<li>Place your enquiry with support from our team.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/bulk-orders\/\"><strong>Bulk Peptides Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shipping-returns\/\"><strong>Shipping &amp; Returns Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/contact-us\/\"><strong>Contact Us Page<\/strong><\/a><br \/>\n<a href=\"https:\/\/wuhantopmiraclepeptides.com\/index.php\/shop-3\/\"><strong>Shop Page<\/strong><\/a><br \/>\n<strong>Quality \/ Compliance Page<\/strong><br \/>\n<strong>Google Search Central<\/strong><br \/>\n<strong>GOV.UK \/ MHRA<\/strong><br \/>\n<strong>ASA \/ CAP Code Section 12<\/strong><br \/>\n<strong>Scientific or ingredient reference source such as PubMed, NCBI, PubChem, CosIng, or an official cosmetic ingredient database<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><span class=\"\">From its design as a biomimetic of the snake venom peptide waglerin\u20111 to its well\u2011characterised role as a reversible antagonist of muscle nicotinic acetylcholine receptors,\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0provides a precisely defined platform for advanced neuromuscular and formulation research. Its ability to modulate neuromuscular signalling through competitive receptor antagonism\u2014supported by computational studies and in vitro research\u2014makes it a valuable addition to any laboratory investigating nAChR pharmacology, neuromuscular signalling, or topical peptide science. By choosing high\u2011purity, lab\u2011verified\u00a0<\/span><strong><span class=\"\">Syn-AKE (200mg) research peptide<\/span><\/strong><span class=\"\">\u00a0from\u00a0<\/span><strong><span class=\"\">Wuhan Top Miracle Peptides<\/span><\/strong><span class=\"\">, you ensure that your research is built on a foundation of quality, reproducibility, and scientific integrity.<\/span><\/p>\n<p class=\"ds-markdown-paragraph\"><strong><span class=\"\">Ready to advance your research with Syn-AKE (200mg)?<\/span><\/strong><span class=\"\">\u00a0Browse our product catalogue, request a wholesale quote, or contact our support team today to discuss your laboratory&#8217;s specific needs.\u00a0<\/span><strong><span class=\"\">Place your order now<\/span><\/strong><span class=\"\">\u00a0and receive GMP\u2011grade Syn\u2011AKE delivered directly to your facility in the UK, EU, or USA.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Buy Syn-AKE (200mg) in the USA. High-purity, lab-tested peptide shipped securely to US, Canada, UK, and Europe for research use.<\/p>\n","protected":false},"featured_media":295,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[18],"product_tag":[574,575,456,455,268,241,590,594,576,232,256,212,266,458,215,592,586,588,589,587,593,591,577,269,578,218,239],"class_list":["post-955","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","product_tag-acetyl-hexapeptide-8-uk","product_tag-argireline-peptide-uk","product_tag-bulk-peptide-supply","product_tag-coa-certificate-of-analysis","product_tag-coa-peptide-supplier-uk","product_tag-cosmetic-peptide-supplier-uk","product_tag-dipeptide-diaminobutyroyl-benzylamide-diacetate-uk","product_tag-osmetic-research-peptide-uk","product_tag-pentapeptide-18-200mg-uk","product_tag-peptide-purity-uk","product_tag-peptide-supplier-europe","product_tag-peptides-for-sale-uk","product_tag-professional-peptide-supplier-uk","product_tag-quality-and-compliance-process","product_tag-research-peptides-europe","product_tag-research-grade-syn-ake","product_tag-snap-8-200mg-uk","product_tag-syn-ake-200mg-peptide","product_tag-syn-ake-cosmetic-peptide","product_tag-syn-ake-peptide-uk","product_tag-syn-ake-supplier-uk","product_tag-synthetic-cosmetic-peptide-uk","product_tag-tripeptide-29-200mg-uk","product_tag-uk-peptide-supplier","product_tag-vialox-pentapeptide-3v-uk","product_tag-where-to-buy-peptides-in-uk","product_tag-wholesale-peptides-uk","first","instock","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product\/955","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/comments?post=955"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media\/295"}],"wp:attachment":[{"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/media?parent=955"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=955"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=955"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/wuhantopmiraclepeptides.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=955"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}