SS-31 Research Peptide: Your Tool for Mitochondrial Bioenergetics & Cardiolipin Stability

Looking for SS-31 Peptide UK from a trusted wholesale peptide supplier? Wuhan Top Miracle Peptides provides research-focused peptide supply support for buyers in the United Kingdom, France, Germany, Spain, Sweden, Italy, the USA, and wider Europe.

SS-31, also known as elamipretide or MTP-131, is a peptide discussed in scientific and pharmaceutical research. This page is written for responsible sourcing, professional enquiries, wholesale support, and documentation review only. It does not provide medical advice, dosage guidance, injection instructions, treatment claims, or personal-use recommendations.

At Wuhan Top Miracle Peptides, we focus on clear product information, COA support where available, responsive service, and reliable communication for UK and international research peptide buyers.

Why SS‑31 Is Different from Ordinary Antioxidants

Most antioxidants work like a fire blanket: they dampen oxidative damage everywhere, often interfering with useful reactive species. SS-31 research peptide works like a precision repair crew. It targets the inner mitochondrial membrane using its alternating aromatic‑cationic structure. Once there, it interacts with cardiolipin to:

• Prevent cardiolipin peroxidation – Oxidised cardiolipin destabilises cristae and breaks electron transport chain supercomplexes.

• Restore cristae architecture – Healthy cristae mean more surface area for ATP synthesis.

• Maintain mitochondrial membrane potential (ΔΨm) – Essential for driving ATP synthase.

• Reduce mitochondrial reactive oxygen species (ROS) – By plugging electron leaks at complexes I and III.

• Inhibit the mitochondrial permeability transition pore (mPTP) – Stops cell death signals from spreading.

This targeted approach means you can study mitochondrial rescue without the confounding effects of broad‑spectrum antioxidants.

Chemical & Physical Specifications

Key Research Applications (Backed by Published Studies)

SS-31 research peptide has been tested in a wide range of disease models — from rare genetic disorders to common age‑related conditions.

Barth Syndrome & Cardiolipin Deficiency

Barth syndrome is an X‑linked disorder caused by mutations in the TAZ gene, leading to abnormal cardiolipin remodelling. In 2025, the FDA approved elamipretide (SS‑31) for Barth syndrome based on the TAZPOWER trial. Patients showed durable improvements in walk distance and quality of life over 168 weeks. This is the first approved therapy targeting cardiolipin directly.

 Heart Failure & Ischemia‑Reperfusion Injury

Preclinical studies show that SS‑31 improves left ventricular function, reduces infarct size, and lowers inflammatory markers (TNF‑α, IL‑6, CRP) without affecting blood pressure. A 2025 study combined SS‑31 with ferrostatin‑1 (SS‑31@Fer‑1) and found it suppressed ferroptosis in cardiomyocytes by maintaining iron homeostasis and improving mitochondrial function.

 Spinal Cord Injury (SCI)

In a mouse thoracic contusion model, SS‑31 significantly improved locomotor recovery, reduced lesion volume, increased neuronal survival, and decreased astrogliosis. A 2025 lipidomics study confirmed that SS‑31 attenuated the reduction in cardiolipin levels after SCI, with dose‑dependent behavioural improvements.

 Parkinson’s Disease & α‑Synuclein Aggregation

A 2026 study showed that SS‑31 displaces α‑synuclein from negatively charged lipid vesicles, inhibits membrane‑induced α‑synuclein aggregation, and restores mitochondrial function in neuroblastoma cells treated with α‑synuclein oligomers. This positions SS‑31 as a potential tool for studying synucleinopathies.

 Idiopathic Pulmonary Fibrosis (IPF)

In a bleomycin‑induced IPF mouse model, SS‑31 reduced fibrosis, inflammation, and extracellular matrix deposition. Mechanistically, it inhibited the Nrf2‑dependent NLRP3 inflammasome, cutting IL‑1β and IL‑18 expression by more than half.

 Reproductive Biology

Adding 1 µM SS‑31 to porcine oocyte maturation medium increased maturation rates from 55% to 78% and blastocyst formation from 2.8% to 7.6%. Treated oocytes had lower ROS, higher glutathione, and better mitochondrial membrane potential.

Reconstitution & Handling Made Simple

Follow these steps to get the most out of your SS-31 research peptide.

Step 1 – Warm up
Bring the sealed vial and your diluent (sterile bacteriostatic water or PBS, pH 5–7) to room temperature. Cold vials can cause condensation inside, which harms the lyophilised powder.

Step 2 – Clean
Wipe both rubber stoppers with a 70% ethanol pad. Let the alcohol evaporate fully.

Step 3 – Reconstitute
Draw the desired volume of diluent (e.g., 1 mL for a 10 mg vial → 10 mg/mL). Insert the needle and slowly inject the liquid against the inner glass wall — never directly onto the powder. Gently swirl the vial. Do not shake.

Step 4 – Aliquot & Store
Divide the reconstituted peptide into single‑use vials. Store at –20°C. Once thawed, keep at 2–8°C and use within 28 days. Avoid repeated freeze‑thaw cycles.

Quick Concentration Table

Storage & Stability at a Glance

Why Choose Wuhan Top Miracle Peptides for SS-31?

We are an authentic licensed peptide supplier based in the United Kingdom, serving research institutions and wholesale clients across Europe and the USA. Here’s what that means for you:

• ≥99% purity confirmed by HPLC and mass spectrometry — every batch.

• GMP‑compliant manufacturing in ISO 13485:2016 facilities.

• Full traceability with batch‑specific Certificates of Analysis (COA).

• Wholesale pricing with flexible volumes — from single vials to bulk orders.

• Fast domestic shipping across the UK (London, Manchester, Birmingham, Edinburgh, etc.) and reliable international delivery to the EU and USA.

• Research‑use only (RUO) — fully compliant with UK and EU regulations.

When you buy SS-31 research peptide from us, you get the same quality trusted by labs across the UK.

FAQ: SS-31 Research Peptide

 What is SS-31 research peptide?
SS‑31 (elamipretide, MTP‑131) is a tetrapeptide (D‑Arg‑Dmt‑Lys‑Phe‑NH₂) that targets the inner mitochondrial membrane by binding to cardiolipin. It improves ATP production, reduces oxidative stress, and maintains cristae structure.

Is SS-31 the same as elamipretide?
Yes. Elamipretide is the generic name, and SS‑31 is the research code. Bendavia is an older clinical name.

 What is the key mechanism of action?
SS‑31 binds to cardiolipin, preventing its oxidation and stabilising electron transport chain supercomplexes. This restores mitochondrial bioenergetics and reduces ROS.

Has SS-31 been approved by the FDA?
Yes. In 2025, the FDA approved elamipretide for Barth syndrome, an ultra‑rare mitochondrial disorder. For all other conditions, it remains a research compound.

 How do I reconstitute SS-31?
Use sterile bacteriostatic water or PBS (pH 5–7). Warm to room temperature, inject slowly against the glass wall, then swirl gently. Never shake.

 What purity does your SS-31 have?
≥99% by HPLC, with a Certificate of Analysis provided for each batch.

Can I buy SS-31 for human use?
No. We sell SS-31 research peptide strictly for in‑vitro and in‑vivo laboratory research only. Not for human or veterinary use.

Wholesale SS-31 Peptide Supply Across the UK and Europe

Wuhan Top Miracle Peptides supports wholesale peptide buyers in the United Kingdom and international markets.

We Ship To:

• United Kingdom
• France
• Germany
• Spain
• Sweden
• Italy
• USA
• Wider Europe

For larger SS-31 orders, contact our team before checkout. This helps confirm current stock, wholesale pricing, documentation, shipping options, and order handling.

Where to Buy SS-31 Peptide in the UK

If you are searching for where to buy SS-31 peptide in the UK, Wuhan Top Miracle Peptides provides a simple process for research-focused and wholesale buyers.

How to Order

1. Review the SS-31 product details.
2. Check the current product label and batch information.
3. Contact our team for availability.
4. Ask about wholesale pricing and COA information.
5. Confirm your shipping country.
6. Place your enquiry with support from our team.

Recommended Buttons

Bulk Peptides Page
Shipping & Returns Page
Contact Us Page
Shop Page
Google Search Central
GOV.UK / MHRA
ASA / CAP Code Section 12
FDA / PubMed / NCBI reference page

Responsible Research Use Notice

SS-31 is listed for research and professional supply purposes only. This page does not provide medical advice, treatment guidance, dosing instructions, injection instructions, disease-related claims, anti-ageing claims, or performance claims.

Avoid public claims that SS-31 improves mitochondrial function, treats Barth syndrome, supports heart health, improves energy, reverses ageing, improves recovery, or treats any medical condition unless you have proper regulatory approval and legally compliant evidence for the exact product and territory. ASA/CAP rules apply high scrutiny to marketing for medicines, medical devices, health-related products, and beauty products.

Whether you are studying Barth syndrome, heart failure, spinal cord injury, Parkinson’s disease, or basic mitochondrial biology, SS-31 research peptide offers a clean, well‑understood tool to stabilise cardiolipin and preserve energy production. The science is robust — backed by PNAS, ScienceDirect, and FDA approval for the Barth syndrome indication. And when you choose Wuhan Top Miracle Peptides, you get verified purity, full documentation, and a partner who understands research needs.

Ready to move forward with SS-31? Browse our online catalogue, request a wholesale quote, or contact our support team. Place your order today and receive laboratory‑ready, GMP‑grade SS‑31 delivered fast across the UK and Europe.